Lorazepam and Sitagliptin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorazepam (lorazepam) and Sitagliptin (sitagliptin). Common drug interactions include proteinuria among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Lorazepam and Sitagliptin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

What is Sitagliptin?

Sitagliptin has active ingredients of sitagliptin. eHealthMe is studying from 3,933 Sitagliptin users. Check the latest studies of Sitagliptin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

77 people who take Lorazepam and Sitagliptin together, and have interactions are studied.

Lorazepam and Sitagliptin drug interactions.

What are the common drug interactions of Lorazepam and Sitagliptin, by gender? *:

female:

  1. Proteinuria (presence of protein in the urine)
  2. Rash papular (redness with papule)
  3. Red cell distribution width increased
  4. Sinusitis (inflammation of sinus)
  5. Tooth fracture
  6. Tri-iodothyronine free decreased
  7. Urinary tract infection
  8. Urine abnormality
  9. Urine ketone body present
  10. Urine leukocyte esterase positive

male:

  1. Diarrhoea
  2. Hypokalaemia (low potassium)
  3. Fatigue (feeling of tiredness)
  4. Interstitial lung disease
  5. Hypotension (abnormally low blood pressure)
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Chest pain
  8. Dysuria (painful or difficult urination)
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Lorazepam and Sitagliptin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug ineffective
  2. Salivary hypersecretion (excess saliva secretion)
  3. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

30-39:

  1. Contusion (a type of hematoma of tissue in which capillaries)
  2. Diarrhoea
  3. Dyspepsia (indigestion)
  4. Eosinophil count increased
  5. Erythema (redness of the skin)
  6. Eye pain
  7. Fatigue (feeling of tiredness)
  8. Feeling hot
  9. Flushing (the warm, red condition of human skin)
  10. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

40-49:

n/a

50-59:

  1. Delirium (wild excitement)
  2. Asthenia (weakness)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Nausea (feeling of having an urge to vomit)
  5. Retching (strong involuntary effort to vomit)
  6. Ankle fracture
  7. Autoimmune neuropathy (disease or dysfunction of one or more peripheral nerves by autoimmune disorders)

60+:

  1. Hypokalaemia (low potassium)
  2. Diarrhoea
  3. Atrial thrombosis (blood clot that develops in an artery)
  4. Dysaesthesia (abnormal sensation)
  5. Feeling cold
  6. Interstitial lung disease
  7. Pain in extremity
  8. Peripheral embolism (sudden interruption of blood flow to an organ or body part)
  9. Peripheral ischaemia (impaired circulation to an extremity)
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 25 people, 32.47%
  2. High Blood Pressure: 14 people, 18.18%
  3. Vasculitis (inflammation of a blood vessel or blood vessels): 13 people, 16.88%
  4. Antisynthetase Syndrome (chronic autoimmune disease of unknown cause): 13 people, 16.88%
  5. Post Procedural Infection: 11 people, 14.29%
  6. Diabetes: 9 people, 11.69%
  7. Neuralgia (pain in one or more nerves): 9 people, 11.69%
  8. Dyslipidaemia (abnormal amount of lipids): 7 people, 9.09%
  9. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 6 people, 7.79%
  10. Cardiac Failure: 6 people, 7.79%

* Approximation only. Some reports may have incomplete information.

Do you take Lorazepam and Sitagliptin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lorazepam and Sitagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sitagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lorazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sitagliptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam and sitagliptin (the active ingredients of Lorazepam and Sitagliptin, respectively), and Lorazepam and Sitagliptin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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