Naprelan and Lorcet-hd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naprelan (naproxen sodium) and Lorcet-hd (acetaminophen; hydrocodone bitartrate). Common drug interactions include vision blurred among females and drug dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Naprelan and Lorcet-hd. It is created by eHealthMe based on reports of 8 people who take the same drugs from the FDA, and is updated regularly.

What is Naprelan?

Naprelan has active ingredients of naproxen sodium. eHealthMe is studying from 731 Naprelan users. Check the latest studies of Naprelan.

What is Lorcet-hd?

Lorcet-hd has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,221 Lorcet-hd users. Check the latest studies of Lorcet-hd.

On Apr, 11, 2026

8 people who take Naprelan and Lorcet-hd together, and have interactions are studied.

Naprelan and Lorcet-hd drug interactions.

What are the common drug interactions of Naprelan and Lorcet-Hd, by gender? *:

female:

Vision blurred
Accident
Blood cholesterol increased
Blood pressure increased
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

male:

Drug dependence
Headache (pain in head)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting
Weight decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerumen impaction
Chills (felling of cold)
Constipation
Drug abuser

What are the common drug interactions of Naprelan and Lorcet-Hd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depression
Diarrhoea
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Irritability
Nausea (feeling of having an urge to vomit)
Suicidal ideation

50-59:

Accident
Blood cholesterol increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Glycosuria (excretion of glucose into the urine)
Type 2 diabetes mellitus
Vision blurred
Visual acuity reduced (reduced clearness of vision)

60+:

Headache (pain in head)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hyperhidrosis (abnormally increased sweating)
Hyperpyrexia (extremely high fever)
Insomnia (sleeplessness)
Irritability
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Malaise (a feeling of general discomfort or uneasiness)
Meningitis listeria (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Muscle contractions involuntary (uncontrolled muscle contraction)

* Approximation only. Some reports may have incomplete information.

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