Lortab and Cefaclor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lortab (acetaminophen; hydrocodone bitartrate) and Cefaclor (cefaclor). Common drug interactions include eating disorder among females and cholelithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Lortab and Cefaclor. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

What is Cefaclor?

Cefaclor has active ingredients of cefaclor. eHealthMe is studying from 2,512 Cefaclor users. Check the latest studies of Cefaclor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

31 people who take Lortab and Cefaclor together, and have interactions are studied.

What are the common drug interactions of Lortab and Cefaclor, by gender? *:

female:

Eating disorder
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Hallucination (an experience involving the perception of something not present)
Impaired driving ability
Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
Muscle injury
Oedema peripheral (superficial swelling)
Skeletal injury (bone and supporting muscle injury)

male:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Headache (pain in head)
Bone fragmentation
Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
Bone swelling
Cardiac failure congestive
Cellulitis (infection under the skin)
Chest pain
Dental caries
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Lortab and Cefaclor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone erosion
Bone swelling
Cellulitis (infection under the skin)
Chills (felling of cold)
Dental caries
Disability
Hypoaesthesia facial (reduced sense of touch or sensation on face)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)

30-39:

n/a

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Dependence
Drug abuse
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Eating disorder
Fall
Fatigue (feeling of tiredness)

50-59:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cellulitis (infection under the skin)
Chills (felling of cold)
Dental caries
Disability
Dysfunctional uterine bleeding
Dyshidrotic eczema (skin condition in which blisters develop on the soles of your feet and/or the palms of hands)
Ear pain
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Gastroenteritis (inflammation of stomach and intestine)

60+:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Headache (pain in head)
Bone fragmentation
Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
Bone swelling
Cardiac failure congestive
Cellulitis (infection under the skin)
Chest pain
Dental caries
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Trismus (reduced opening of the jaws): 16 people, 51.61%
Multiple Myeloma (cancer of the plasma cells): 16 people, 51.61%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 19.35%
Urinary Tract Infection: 5 people, 16.13%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 16.13%
Sinusitis (inflammation of sinus): 5 people, 16.13%
Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 16.13%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 16.13%
Mixed Incontinence (a combination of stress and urge incontinence): 5 people, 16.13%
Insomnia (sleeplessness): 5 people, 16.13%

* Approximation only. Some reports may have incomplete information.

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