Losartan potassium and Sovaldi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan potassium (losartan potassium) and Sovaldi (sofosbuvir). Common drug interactions include ascites among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan potassium and Sovaldi. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan potassium?

Losartan potassium has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 51,511 Losartan potassium users. Check the latest studies of Losartan potassium.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.



On Jul, 12, 2026

16 people who take Losartan potassium and Sovaldi together, and have interactions are studied.

Losartan potassium and Sovaldi drug interactions.

What are the common drug interactions of Losartan Potassium and Sovaldi, by gender? *:

female:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Cardiac failure congestive
  4. Hepatic failure (liver failure)
  5. Hyperthyroidism (over activity of the thyroid gland)
  6. Mitral valve incompetence (inefficient heart valve)
  7. Rash

male:

  1. Asthenia (weakness)
  2. Chronic kidney disease
  3. Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
  4. Blood potassium increased
  5. Cardiovascular disorder (heart diseases)
  6. Chills (felling of cold)
  7. Drug ineffective
  8. Drug intolerance (drug sensitivity)
  9. Dyspnoea (difficult or laboured respiration)
  10. Ear discomfort

What are the common drug interactions of Losartan Potassium and Sovaldi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Depression
  2. Anaemia (lack of blood)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Cardiovascular disorder (heart diseases)
  6. Chronic kidney disease
  7. Emotional distress
  8. Gout (uric acid crystals building up in the body)
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Hypertensive crisis

60+:

  1. Hepatic failure (liver failure)
  2. Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
  3. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  4. Lower respiratory tract infection
  5. Mitral valve incompetence (inefficient heart valve)
  6. Productive cough
  7. Pyrexia (fever)
  8. Rash
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Hepatitis C: 9 people, 56.25%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
  3. Hiv Infection: 2 people, 12.50%
  4. Diabetes: 2 people, 12.50%
  5. Oedema (fluid collection in tissue): 2 people, 12.50%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 12.50%
  7. Muscle Spasms (muscle contraction): 2 people, 12.50%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
  9. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 2 people, 12.50%
  10. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan potassium and Sovaldi?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Losartan potassium and Sovaldi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Losartan potassium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sovaldi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Losartan potassium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sovaldi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium and sofosbuvir (the active ingredients of Losartan potassium and Sovaldi, respectively), and Losartan potassium and Sovaldi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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