Losartan and Accolate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Accolate (zafirlukast). Common drug interactions include renal failure among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Accolate. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.

What is Accolate?

Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.

On Jul, 14, 2026

48 people who take Losartan and Accolate together, and have interactions are studied.

Losartan and Accolate drug interactions.

What are the common drug interactions of Losartan and Accolate, by gender? *:

female:

Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Ear infection
Eye infection
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Abasia (inability to walk)
Abdominal pain

male:

Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Recurrent cancer (repeated cancer)
Anaemia macrocytic (a macrocytic class of anaemia)
Aortic valve incompetence
Aphakia (absence of the lens of the eye)
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Back pain
Bifascicular block (conduction abnormality in the heart where two of the three main fascicles of the his/purkinje system are blocked)

What are the common drug interactions of Losartan and Accolate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac disorder
Drug hypersensitivity
Recurrent cancer (repeated cancer)
Acute respiratory failure
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Back pain

50-59:

Night sweats (sweating in night)
Reaction to drug excipients
Renal disorder (kidney disease)
Renal injury (kidney injury)
Restlessness (not able to rest)
Spinal fracture (fracture in one of vertebrae)
Urine sodium decreased
Vitreous floaters (spots before the eyes)
Nausea (feeling of having an urge to vomit)
Headache (pain in head)

60+:

Malaise (a feeling of general discomfort or uneasiness)
Concussion (short loss of normal brain function in response to a head injury)
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
Carotid artery disease
Coagulopathy (blood's ability to clot is impaired)
Fatigue (feeling of tiredness)
Influenza
Infusion site swelling
Laryngitis (inflammation of the larynx)
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 12.50%
Diabetes: 4 people, 8.33%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 6.25%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.25%
Immune System Disorder: 3 people, 6.25%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 6.25%
Hypersensitivity: 3 people, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.25%
Depression: 3 people, 6.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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