Losartan and Bextra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan (losartan potassium) and Bextra (valdecoxib). Common drug interactions include infection among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan and Bextra. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

On Jul, 07, 2026

43 people who take Losartan and Bextra together, and have interactions are studied.

What are the common drug interactions of Losartan and Bextra, by gender? *:

female:

Infection
Influenza
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Joint instability (a condition in which the joints aren't sufficiently supported)
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Lung cancer metastatic (lung cancer spreads to other parts)
Lung neoplasm malignant (cancer tumour of lung)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Multiple fractures
Muscle spasms (muscle contraction)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dyspnoea (difficult or laboured respiration)
Influenza like illness
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Stomach discomfort (pain in abdomen)
Venous angioma of brain (benign tumour in the brain)
Vertebral artery stenosis (abnormal narrowing of vertebral artery)
Activities of daily living impaired
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Losartan and Bextra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood pressure decreased
Dyspnoea (difficult or laboured respiration)
Bradycardia (abnormally slow heart action)

40-49:

Nephrogenic anaemia (anaemia due to kidney disease)
Panic attack
Stress
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematochezia (passage of stools containing blood)
Heart rate increased
Influenza like illness

50-59:

Asthenia (weakness)
Gastric disorder (disease of stomach)
Intervertebral disc protrusion (spinal disc protrusion)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Abasia (inability to walk)
Abdominal pain
Burning sensation
Central nervous system infection (infection of brain or spinal cord)
Chest pain
Chronic kidney disease

60+:

Chronic kidney disease
Drug hypersensitivity
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in extremity
Postoperative infection
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Venous angioma of brain (benign tumour in the brain)
Vertebral artery stenosis (abnormal narrowing of vertebral artery)
Abdominal pain upper

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 12 people, 27.91%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 27.91%
Diabetes: 8 people, 18.60%
High Blood Cholesterol: 8 people, 18.60%
Asthma: 7 people, 16.28%
Multiple Allergies (allergy to multiple agents): 6 people, 13.95%
Back Pain: 6 people, 13.95%
Chest Pain: 6 people, 13.95%
Depression: 5 people, 11.63%
Blood Pressure Abnormal: 4 people, 9.30%

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and Bextra?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously