Losartan and Versed drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Losartan (losartan potassium) and Versed (midazolam hydrochloride). Common drug interactions include bursitis among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Losartan and Versed. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.
What is Losartan?
Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.
What is Versed?
Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.
74 people who take Losartan and Versed together, and have interactions are studied.

What are the common drug interactions of Losartan and Versed, by gender? *:
female:
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cardiac murmur (an heart sound in valve abnormality)
- Cardiomegaly (increased size of heart than normal)
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Decreased interest
- Deformity (disfigurement)
- Dental caries
- Depression
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chest pain
- Colitis ulcerative (inflammation of colon with ulcer)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Memory impairment
- Quality of life decreased
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Acute myocardial infarction (acute heart attack)
What are the common drug interactions of Losartan and Versed, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anxiety
- Emotional distress
- Fear
- Pain
- Stress
- Blindness
- Colitis ulcerative (inflammation of colon with ulcer)
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Memory impairment
50-59:
- Gout (uric acid crystals building up in the body)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fluid overload (too much fluid in the blood)
- Neuropathy peripheral (surface nerve damage)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Abdominal distension
- Actinic keratosis (skin disease due to sun exposure)
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
- Aortic valve disease
60+:
- Renal failure (kidney dysfunction)
- Anxiety
- Stress
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Asthenia (weakness)
- Blood potassium increased
- Blood pressure fluctuation
- Blood sodium decreased
- Chest pain
- Chronic kidney disease
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 22 people, 29.73%
- Pain: 14 people, 18.92%
- Multiple Myeloma (cancer of the plasma cells): 12 people, 16.22%
- High Blood Cholesterol: 11 people, 14.86%
- Infection: 7 people, 9.46%
- Diabetes: 7 people, 9.46%
- Type 2 Diabetes: 6 people, 8.11%
- Nausea (feeling of having an urge to vomit): 5 people, 6.76%
- Indigestion: 5 people, 6.76%
- Headache (pain in head): 5 people, 6.76%
* Approximation only. Some reports may have incomplete information.
Do you take Losartan and Versed?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Losartan and Versed:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Losartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Versed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Losartan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Versed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on losartan potassium and midazolam hydrochloride (the active ingredients of Losartan and Versed, respectively), and Losartan and Versed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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