Lotrel and Hydrocortisone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lotrel (amlodipine besylate; benazepril hydrochloride) and Hydrocortisone (hydrocortisone). Common drug interactions include fatigue among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Lotrel and Hydrocortisone. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

On Jul, 16, 2026

20 people who take Lotrel and Hydrocortisone together, and have interactions are studied.

Lotrel and Hydrocortisone drug interactions.

What are the common drug interactions of Lotrel and Hydrocortisone, by gender? *:

female:

Fatigue (feeling of tiredness)
Feeling jittery
Fluid overload (too much fluid in the blood)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gallbladder operation
Gastroenteritis (inflammation of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gingival abscess (pus in gums)
Headache (pain in head)
Heart rate decreased

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dehydration (dryness resulting from the removal of water)
Cardiomegaly (increased size of heart than normal)
Diarrhoea
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Angiocalcinosis
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac murmur (an heart sound in valve abnormality)

What are the common drug interactions of Lotrel and Hydrocortisone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Infective tenosynovitis (infective inflammation of a tendon sheath)
Rotator cuff repair
Tendon operation
Vertebral injury (spinal cord injury)

50-59:

Heart rate irregular
Hot flush (sudden feelings of heat)
Hyperkalaemia (damage to or disease of the kidney)
Hyperlipidaemia (presence of excess lipids in the blood)
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Hypokalaemia (low potassium)
Hypophagia (reduced food intake)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Hypoxia (low oxygen in tissues)
Ill-defined disorder

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dehydration (dryness resulting from the removal of water)
Cardiomegaly (increased size of heart than normal)
Diarrhoea
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Angiocalcinosis
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac murmur (an heart sound in valve abnormality)

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 3 people, 15.00%
Metastases To Bone (cancer spreads to bone): 3 people, 15.00%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 10.00%
Nosebleed (bleeding from nose): 2 people, 10.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 10.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 10.00%
Depression: 2 people, 10.00%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 10.00%
Rosacea (a skin condition that causes facial redness): 2 people, 10.00%
Androgenetic Alopecia (common form of hair loss): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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