Lotrel and Propofol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lotrel (amlodipine besylate; benazepril hydrochloride) and Propofol (propofol). Common drug interactions include anhedonia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Lotrel and Propofol. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 38,224 Propofol users. Check the latest studies of Propofol.

On Jul, 15, 2026

26 people who take Lotrel and Propofol together, and have interactions are studied.

What are the common drug interactions of Lotrel and Propofol, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Fear
Multi-organ failure (multisystem organ failure)
Nervousness
Psychiatric symptom
Abdominal pain
Abdominal pain upper
Alanine aminotransferase increased
Alopecia (absence of hair from areas of the body)

male:

Anxiety
Injury
Decreased interest
Dental caries
Depression
Dysuria (painful or difficult urination)
Erectile dysfunction
Fatigue (feeling of tiredness)
Gingival abscess (pus in gums)
Gingival bleeding (bleeding gums)

What are the common drug interactions of Lotrel and Propofol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Malignant neoplasm progression (cancer tumour came back)
Proctalgia (pain in the rectum)
Alanine aminotransferase increased
Blood chloride decreased
Blood sodium decreased
Chills (felling of cold)
Gamma-glutamyltransferase increased
Haematocrit decreased
Haemoglobin decreased
Mucosal inflammation (infection of mucous membrane)

50-59:

Renal failure (kidney dysfunction)
Anxiety
Emotional distress
Injury
Renal injury (kidney injury)
Chronic kidney disease
Dyspepsia (indigestion)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain

60+:

Anxiety
Emotional distress
Renal failure acute (rapid kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Multi-organ failure (multisystem organ failure)
Nervousness
Psychiatric symptom
Anaemia (lack of blood)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

What are the existing conditions these people have? *

Weakness: 8 people, 30.77%
Prostate Cancer: 8 people, 30.77%
Pain: 8 people, 30.77%
Hypoaesthesia (reduced sense of touch or sensation): 8 people, 30.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 19.23%
Blood Cholesterol Decreased: 3 people, 11.54%
Enlarged Prostate: 3 people, 11.54%
Heart Attack: 3 people, 11.54%
High Blood Cholesterol: 3 people, 11.54%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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