Lovenox and Sirolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lovenox (enoxaparin sodium) and Sirolimus (sirolimus). Common drug interactions include hyponatraemia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Lovenox and Sirolimus. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

On Jul, 15, 2026

51 people who take Lovenox and Sirolimus together, and have interactions are studied.

Lovenox and Sirolimus drug interactions.

What are the common drug interactions of Lovenox and Sirolimus, by gender? *:

female:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Aspartate aminotransferase increased

male:

Diarrhoea
Pneumonia
Hypotension (abnormally low blood pressure)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)
Oral candidiasis (fungal infection of mouth)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Anxiety
Asthenia (weakness)

What are the common drug interactions of Lovenox and Sirolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Haematuria (presence of blood in urine)
Haemoglobinuria (the presence of free haemoglobin in the urine)

10-19:

n/a

20-29:

Hypotension (abnormally low blood pressure)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain upper
Acne (skin problems that cause pimples)
Acute respiratory failure

30-39:

n/a

40-49:

Pneumonia
Colonic pseudo-obstruction (severe impairment in the ability of the intestines to push food through)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematoma (collection of blood outside the blood vessels)
Leukocytosis (increased white blood cells)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Muscular weakness (muscle weakness)
Pleural effusion (water on the lungs)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Pyrexia (fever)

50-59:

Hypovolaemia (a decreased volume of circulating blood in the body)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Intervertebral disc protrusion (spinal disc protrusion)
Lipoatrophy (localized loss of fat tissue)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Mass
Metastases to bone (cancer spreads to bone)
Mitral valve incompetence (inefficient heart valve)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myeloma recurrence (recurrence of cancer of the plasma cells - a kind of white blood cell)

60+:

Abdominal discomfort
Dysphonia (speech disorder attributable to a disorder of phonation)
Cushingoid (obesity and weakening of the muscles)
Dehydration (dryness resulting from the removal of water)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug ineffective
Dysstasia (difficulty in standing)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Faecal incontinence (a lack of control over passing stool)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 13 people, 25.49%
High Blood Pressure: 11 people, 21.57%
Thrombosis (formation of a blood clot inside a blood vessel): 5 people, 9.80%
Immunodeficiency Disorders: 4 people, 7.84%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 4 people, 7.84%
Renal Cell Carcinoma (a kidney cancer): 3 people, 5.88%
Pain: 3 people, 5.88%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 3 people, 5.88%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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