Lovenox and Votrient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lovenox (enoxaparin sodium) and Votrient (pazopanib hydrochloride). Common drug interactions include dyspepsia among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Lovenox and Votrient. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.



On Jul, 13, 2026

65 people who take Lovenox and Votrient together, and have interactions are studied.

Lovenox and Votrient drug interactions.

What are the common drug interactions of Lovenox and Votrient, by gender? *:

female:

  1. Dyspepsia (indigestion)
  2. Dyspnoea (difficult or laboured respiration)
  3. Eosinophil count decreased
  4. Fatigue (feeling of tiredness)
  5. Frequent bowel movements
  6. Gingival pain (gum pain)
  7. Haemorrhage (bleeding)
  8. Mean cell haemoglobin concentration decreased (less concentration of haemoglobin in a given volume of packed red blood cells)
  9. Nausea (feeling of having an urge to vomit)
  10. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Death
  4. Dyspnoea (difficult or laboured respiration)
  5. Fatigue (feeling of tiredness)
  6. Hilar lymphadenopathy (disease of the lymph nodes due to infection)
  7. Laryngeal oedema (swelling of larynx)
  8. Laryngitis (inflammation of the larynx)
  9. Lip ulceration (ulcer of lip)
  10. Malignant neoplasm progression (cancer tumour came back)

What are the common drug interactions of Lovenox and Votrient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cardiac arrest
  2. Drug ineffective
  3. Epistaxis (bleed from the nose)
  4. Hip arthroplasty

40-49:

  1. Death
  2. Blood pressure increased
  3. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  4. Chest pain
  5. Cough
  6. Pleural effusion (water on the lungs)
  7. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  8. Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

  1. Abdominal pain
  2. C-reactive protein increased
  3. Fatigue (feeling of tiredness)
  4. Haematemesis (vomiting of blood)
  5. Haematuria (presence of blood in urine)
  6. International normalised ratio increased
  7. Intervertebral disc degeneration (spinal disc degeneration)
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  9. Stridor
  10. Therapeutic response decreased (less preventive response)

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Death
  3. Blood pressure diastolic decreased
  4. Dehydration (dryness resulting from the removal of water)
  5. Drug ineffective
  6. Dyspepsia (indigestion)
  7. Eosinophil count decreased
  8. Frequent bowel movements
  9. Gingival pain (gum pain)
  10. Haemorrhage (bleeding)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 26 people, 40.00%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 6.15%
  3. Neoplasm Malignant (cancer tumour): 4 people, 6.15%

* Approximation only. Some reports may have incomplete information.

Do you take Lovenox and Votrient?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lovenox and Votrient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lovenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Votrient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lovenox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Votrient and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on enoxaparin sodium and pazopanib hydrochloride (the active ingredients of Lovenox and Votrient, respectively), and Lovenox and Votrient (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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