Lutein and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lutein (lutein) and Ultram (tramadol hydrochloride). Common drug interactions include oedema peripheral among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Lutein and Ultram. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Lutein?

Lutein has active ingredients of lutein. It is often used in macular degeneration. eHealthMe is studying from 7,461 Lutein users. Check the latest studies of Lutein.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

50 people who take Lutein and Ultram together, and have interactions are studied.

What are the common drug interactions of Lutein and Ultram, by gender? *:

female:

Oedema peripheral (superficial swelling)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Road traffic accident
Stress
Transient global amnesia (a temporary short-term memory loss)
Weight decreased
Death
Abdominal pain
Arthralgia (joint pain)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Hypotension (abnormally low blood pressure)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Renal failure (kidney dysfunction)
Agitation (state of anxiety or nervous excitement)
Balance disorder
Blood creatinine increased
Blood disorder
Blood uric acid increased

What are the common drug interactions of Lutein and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypoaesthesia (reduced sense of touch or sensation)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Stress
Urinary tract infection
Abdominal pain
Colitis (inflammation of colon)
Diarrhoea

40-49:

n/a

50-59:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Medical device complication
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

60+:

Fall
Foot fracture
Muscle spasms (muscle contraction)
Pneumonia
Vomiting
Chest pain
Confusional state
Dehydration (dryness resulting from the removal of water)
Febrile neutropenia (fever with reduced white blood cells)
Hypokalaemia (low potassium)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 12.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 10.00%
Nausea (feeling of having an urge to vomit): 4 people, 8.00%
Muscle Spasms (muscle contraction): 4 people, 8.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.00%
Drowsiness: 4 people, 8.00%
Asthma: 4 people, 8.00%
Osteoporosis (bones weak and more likely to break): 3 people, 6.00%
Migraine (headache): 3 people, 6.00%
Insomnia (sleeplessness): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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