Luvox and Donepezil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Luvox (fluvoxamine maleate) and Donepezil (donepezil hydrochloride). Common drug interactions include grand mal convulsion among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Luvox and Donepezil. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Luvox?

Luvox has active ingredients of fluvoxamine maleate. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 13,439 Luvox users. Check the latest studies of Luvox.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

On Jul, 26, 2026

66 people who take Luvox and Donepezil together, and have interactions are studied.

What are the common drug interactions of Luvox and Donepezil, by gender? *:

female:

Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haematuria (presence of blood in urine)
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Hydronephrosis (water inside the kidney)
Hyperglycaemia (high blood sugar)
Hyperthermia (body temperature greatly above normal)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hyporeflexia (a condition of below normal or absent reflexes)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

male:

Nausea (feeling of having an urge to vomit)
Hypertension (high blood pressure)
Freezing phenomenon
General physical health deterioration (weak health status)
Mobility decreased (ability to move is reduced)
Muscle rigidity (muscle stiffness)
Parkinson's disease
Vertigo
Agitation (state of anxiety or nervous excitement)
Cold sweat

What are the common drug interactions of Luvox and Donepezil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hallucination (an experience involving the perception of something not present)
Glycosylated haemoglobin increased
Vomiting

40-49:

n/a

50-59:

Sedation
Somnolence (a state of near-sleep, a strong desire for sleep)
Theft
Tremor (trembling or shaking movements in one or more parts of your body)
Agitation (state of anxiety or nervous excitement)
Death
Dermatillomania (skin picking disorders)
Feeling hot
Flushing (the warm, red condition of human skin)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)

60+:

Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Nausea (feeling of having an urge to vomit)
Urinary tract infection
Dehydration (dryness resulting from the removal of water)
Hypertension (high blood pressure)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Unresponsive to stimuli
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Libido increased (increased sexual urge to have sex)
Urinary retention (the inability to completely or partially empty the bladder)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 14 people, 21.21%
Depression: 10 people, 15.15%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 10 people, 15.15%
Bipolar Disorder (mood disorder): 6 people, 9.09%
Parkinson's Disease: 5 people, 7.58%
Psychotic Disorder: 4 people, 6.06%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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