Lynparza and Lorazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lynparza (olaparib) and Lorazepam (lorazepam). Common drug interactions include restlessness among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Lynparza and Lorazepam. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Lynparza?

Lynparza has active ingredients of olaparib. eHealthMe is studying from 12,322 Lynparza users. Check the latest studies of Lynparza.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

63 people who take Lynparza and Lorazepam together, and have interactions are studied.

Lynparza and Lorazepam drug interactions.

What are the common drug interactions of Lynparza and Lorazepam, by gender? *:

female:

Restlessness (not able to rest)
Salivary hypersecretion (excess saliva secretion)
Sleep disorder
Somnolence (a state of near-sleep, a strong desire for sleep)
Tinnitus (a ringing in the ears)
Balance disorder
Blood pressure increased
Cardiomegaly (increased size of heart than normal)
Chest pain
Dehydration (dryness resulting from the removal of water)

male:

Pleural effusion (water on the lungs)
Pneumonia
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gastroenteritis (inflammation of stomach and intestine)
Heart rate increased
Hospitalisation
Intervertebral disc disorder (spinal disc disorder)
Malignant neoplasm progression (cancer tumour came back)
Myalgia (muscle pain)

What are the common drug interactions of Lynparza and Lorazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nausea (feeling of having an urge to vomit)
Vomiting
Back pain
Death
Diarrhoea
Fatigue (feeling of tiredness)
Abdominal pain upper
Apathy
Arthralgia (joint pain)
Asthenia (weakness)

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hallucination (an experience involving the perception of something not present)
Somnolence (a state of near-sleep, a strong desire for sleep)
Urticaria (rash of round, red welts on the skin that itch intensely)
Death
Diarrhoea
Rash

60+:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Diarrhoea
Malignant neoplasm progression (cancer tumour came back)
Myalgia (muscle pain)
Asthenia (weakness)
Muscle spasms (muscle contraction)
Abdominal discomfort
Fall
Metastases to liver (cancer spreads to liver)

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 32 people, 50.79%
Sleep Disorder: 10 people, 15.87%
Nausea (feeling of having an urge to vomit): 8 people, 12.70%
Pain: 6 people, 9.52%
High Blood Cholesterol: 6 people, 9.52%
Constipation: 5 people, 7.94%
Neuropathy Peripheral (surface nerve damage): 4 people, 6.35%
Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 4 people, 6.35%
Insomnia (sleeplessness): 4 people, 6.35%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

Do you take Lynparza and Lorazepam?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously