Lyrica and Ticagrelor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lyrica (pregabalin) and Ticagrelor (ticagrelor). Common drug interactions include diabetic foot among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Lyrica and Ticagrelor. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

What is Ticagrelor?

Ticagrelor has active ingredients of ticagrelor. eHealthMe is studying from 8,499 Ticagrelor users. Check the latest studies of Ticagrelor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

18 people who take Lyrica and Ticagrelor together, and have interactions are studied.

Lyrica and Ticagrelor drug interactions.

What are the common drug interactions of Lyrica and Ticagrelor, by gender? *:

female:

Diabetic foot
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Vomiting
Cardiac arrest
Hypotension (abnormally low blood pressure)
Blood immunoglobulin e increased
Cardiac disorder
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Dyspnoea (difficult or laboured respiration)

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Asthenia (weakness)
Dizziness
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Melaena (the passage of black, tarry stools)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Lyrica and Ticagrelor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood immunoglobulin e increased
Cardiac disorder
Constipation
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Febrile neutropenia (fever with reduced white blood cells)
Headache (pain in head)
Lower respiratory tract infection
Lymphocyte count decreased
Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood)
Nausea (feeling of having an urge to vomit)

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Diabetic foot
Impaired work ability

60+:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Asthenia (weakness)
Cardiac failure congestive
Chronic kidney disease
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dizziness
Erythema (redness of the skin)
Feeling hot
Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

Diabetes: 7 people, 38.89%
High Blood Pressure: 6 people, 33.33%
Pain: 6 people, 33.33%
High Blood Cholesterol: 4 people, 22.22%
Chest Pain: 4 people, 22.22%
Blockage Of Leg Arteries: 3 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.11%
Depression: 2 people, 11.11%
Gout (uric acid crystals building up in the body): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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