Lysteda and Xyrem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lysteda (tranexamic acid) and Xyrem (sodium oxybate). Common drug interactions include gout among females.
The phase IV clinical study analyzes what interactions people have when they take Lysteda and Xyrem. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Lysteda?
Lysteda has active ingredients of tranexamic acid. It is often used in menstrual periods - heavy, prolonged, or irregular. eHealthMe is studying from 289 Lysteda users. Check the latest studies of Lysteda.
What is Xyrem?
Xyrem has active ingredients of sodium oxybate. It is often used in narcolepsy. eHealthMe is studying from 81,487 Xyrem users. Check the latest studies of Xyrem.
14 people who take Lysteda and Xyrem together, and have interactions are studied.

What are the common drug interactions of Lysteda and Xyrem, by gender? *:
female:
- Gout (uric acid crystals building up in the body)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Colitis ulcerative (inflammation of colon with ulcer)
- Hysterectomy
- Nausea (feeling of having an urge to vomit)
- Nephrolithiasis (calculi in the kidneys)
- Small intestinal obstruction (blockage in small intestine)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Trigger finger
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
male:
n/a
What are the common drug interactions of Lysteda and Xyrem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Gout (uric acid crystals building up in the body)
- Hysterectomy
- Vomiting
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Panic attack
- Seasonal allergy (allergic condition due to certain season)
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
- Headache (pain in head)
- Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
- Plantar fasciitis (painful inflammatory process of the plantar fascia)
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 50.00%
- Drowsiness: 2 people, 14.29%
- Depression: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Lysteda and Xyrem?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lysteda and Xyrem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lysteda:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xyrem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lysteda and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xyrem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tranexamic acid and sodium oxybate (the active ingredients of Lysteda and Xyrem, respectively), and Lysteda and Xyrem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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