Lysteda and Zyrtec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lysteda (tranexamic acid) and Zyrtec (cetirizine hydrochloride). Common drug interactions include middle insomnia among females and conjunctivitis allergic among males.

The phase IV clinical study analyzes what interactions people have when they take Lysteda and Zyrtec. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Lysteda?

Lysteda has active ingredients of tranexamic acid. It is often used in menstrual periods - heavy, prolonged, or irregular. eHealthMe is studying from 289 Lysteda users. Check the latest studies of Lysteda.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,620 Zyrtec users. Check the latest studies of Zyrtec.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

15 people who take Lysteda and Zyrtec together, and have interactions are studied.

What are the common drug interactions of Lysteda and Zyrtec, by gender? *:

female:

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Poor quality sleep
Retching (strong involuntary effort to vomit)
Choking sensation (feeling of obstruction in respiratory system)
Cholecystitis acute (rapid infection of gallbladder)
Cholecystitis infective (infection of gallbladder capable to infect other organs)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Dysgraphia (impaired ability to learn to write)

male:

Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)
Eye irritation
Eye pain
Eye pruritus (eye itching)
Eye swelling
Lacrimation increased

What are the common drug interactions of Lysteda and Zyrtec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective
Hunger
Initial insomnia (feeling of inadequate or poor-quality sleep)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Poor quality sleep
Retching (strong involuntary effort to vomit)

30-39:

Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Pain
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Procedural haemorrhage (procedural bleeding)
Urinary tract infection
Uterine perforation (accidental puncture of the uterus)
Vomiting
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Eye irritation

40-49:

n/a

50-59:

Hereditary angioedema (recurrent episodes of severe swelling)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 53.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 46.67%
Cystic Fibrosis (disease of the secretary glands): 3 people, 20.00%
Vitamin B Complex Deficiency: 1 person, 6.67%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 6.67%
Allergy To Plants: 1 person, 6.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 6.67%
Asthma: 1 person, 6.67%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 6.67%
Birth Control: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lysteda and Zyrtec?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously