Macrodantin and Provera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Macrodantin (nitrofurantoin, macrocrystalline) and Provera (medroxyprogesterone acetate). Common drug interactions include amnesia among females.

The phase IV clinical study analyzes what interactions people have when they take Macrodantin and Provera. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Macrodantin?

Macrodantin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 3,755 Macrodantin users. Check the latest studies of Macrodantin.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

On Jul, 12, 2026

41 people who take Macrodantin and Provera together, and have interactions are studied.

Macrodantin and Provera drug interactions.

What are the common drug interactions of Macrodantin and Provera, by gender? *:

female:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Hypoaesthesia (reduced sense of touch or sensation)
Decreased interest
Disturbance in attention
Feelings of worthlessness
Initial insomnia (feeling of inadequate or poor-quality sleep)
Intentional self-injury
Mood altered (changes in mood)
Nightmare (unpleasant dream)
Sleep disorder

male:

n/a

What are the common drug interactions of Macrodantin and Provera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

20-29:

Drug ineffective

30-39:

Post-traumatic stress disorder
Rib fracture
Suicidal ideation
Tremor (trembling or shaking movements in one or more parts of your body)
Uterine polyp (a mass in the inner lining of the uterus)
Vaginal haemorrhage (vaginal bleeding)
Vertigo
Viral infection
Vulval disorder
Weight increased

40-49:

Constipation
Fall
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Breast pain
Chest pain
Dry mouth
Fracture
Headache (pain in head)

50-59:

Burning sensation
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fall
Hip fracture
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Abdominal pain
Breast cancer female
Dizziness

60+:

Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Depression
Dizziness
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Fibrocystic breast disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Depression: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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