Magnesium gluconate and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Magnesium gluconate (magnesium) and Morphine (morphine sulfate). Common drug interactions include tooth extraction among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Magnesium gluconate and Morphine. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Magnesium gluconate?

Magnesium gluconate has active ingredients of magnesium. eHealthMe is studying from 2,286 Magnesium gluconate users. Check the latest studies of Magnesium gluconate.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.



On Aug, 10, 2026

78 people who take Magnesium gluconate and Morphine together, and have interactions are studied.

Magnesium gluconate and Morphine drug interactions.

What are the common drug interactions of Magnesium Gluconate and Morphine, by gender? *:

female:

  1. Tooth extraction
  2. Injection site erythema (redness at injection site)
  3. Pyrexia (fever)
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Injection site pruritus (severe itching at injection site)
  6. Metastases to bone (cancer spreads to bone)
  7. Metastases to lung (cancer spreads to lung)
  8. Weight decreased
  9. Abdominal pain
  10. Hospitalisation

male:

  1. Chronic kidney disease
  2. Alopecia (absence of hair from areas of the body)
  3. Superior vena cava syndrome (obstruction of blood flow through the superior vena cava)
  4. Weight decreased
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Bone metabolism disorder
  8. Emotional distress
  9. Renal failure (kidney dysfunction)
  10. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)

What are the common drug interactions of Magnesium Gluconate and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Cerebral haemorrhage (bleeding within the brain)
  2. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal hernia
  2. Alopecia (absence of hair from areas of the body)
  3. Anxiety
  4. Asthenia (weakness)
  5. Atelectasis (partial or complete collapse of the lung)
  6. Body temperature decreased
  7. Bone disorder
  8. Cellulitis (infection under the skin)
  9. Chest pain
  10. Chills (felling of cold)

40-49:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Chest pain
  3. Disease progression
  4. Heart rate increased
  5. Large intestinal obstruction
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Pleural effusion (water on the lungs)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  10. Vertebrobasilar insufficiency (decrease of blood flow in the vertebral or basilar arteries due to atherosclerosis or compression placed on the external wall of the arteries)

50-59:

  1. Tumour pain
  2. Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
  3. Alcoholic seizure
  4. Alopecia (absence of hair from areas of the body)
  5. Blood bilirubin increased
  6. Blood lactate dehydrogenase increased
  7. Chest discomfort
  8. Dysgeusia (disorder of the sense of taste)
  9. Epstein-barr virus infection
  10. Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)

60+:

  1. Weight decreased
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Fatigue (feeling of tiredness)
  4. Alopecia (absence of hair from areas of the body)
  5. Cardiogenic shock (inadequate circulation of blood)
  6. Constipation
  7. Decreased appetite
  8. Epistaxis (bleed from the nose)
  9. Neoplasm progression (growth of tumour)
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 10 people, 12.82%
  2. Breast Cancer: 10 people, 12.82%
  3. Diarrhea: 10 people, 12.82%
  4. Nausea (feeling of having an urge to vomit): 9 people, 11.54%
  5. High Blood Pressure: 9 people, 11.54%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 11.54%
  7. Stress And Anxiety: 7 people, 8.97%
  8. Back Pain: 7 people, 8.97%
  9. Oedema (fluid collection in tissue): 6 people, 7.69%
  10. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Magnesium gluconate and Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Magnesium gluconate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium gluconate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on magnesium and morphine sulfate (the active ingredients of Magnesium gluconate and Morphine, respectively), and Magnesium gluconate and Morphine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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