Magnesium and Alkeran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Magnesium (magnesium) and Alkeran (melphalan). Common drug interactions include pain among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Magnesium and Alkeran. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,144 Magnesium users. Check the latest studies of Magnesium.

What is Alkeran?

Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users. Check the latest studies of Alkeran.



On Jul, 20, 2026

57 people who take Magnesium and Alkeran together, and have interactions are studied.

Magnesium and Alkeran drug interactions.

What are the common drug interactions of Magnesium and Alkeran, by gender? *:

female:

  1. Pain
  2. Weight decreased
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Impaired healing
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Anaemia (lack of blood)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Diarrhoea
  10. Arthralgia (joint pain)

male:

  1. Anaemia (lack of blood)
  2. Neuropathy peripheral (surface nerve damage)
  3. Tendonitis (a condition that causes pain and swelling of tendons)
  4. Fall
  5. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  6. Neutropenia (an abnormally low number of neutrophils)
  7. Proteinuria (presence of protein in the urine)
  8. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Arthralgia (joint pain)

What are the common drug interactions of Magnesium and Alkeran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Hepatic vein occlusion (blockage of the hepatic vein)
  3. Arrhythmia (irregular heartbeat)
  4. Cardiac failure
  5. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  6. Hyperglycaemia (high blood sugar)
  7. Pericardial effusion (fluid around the heart)
  8. Pulmonary oedema (fluid accumulation in the lungs)
  9. Respiratory disorder (respiratory disease)
  10. Oedema (fluid collection in tissue)

20-29:

  1. Mucous membrane disorder (disease of mucous membrane)

30-39:

  1. C-reactive protein increased
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Anaemia (lack of blood)
  4. Aortic arteriosclerosis (hardening of the aortic arteries)
  5. Aortic valve incompetence
  6. Arthralgia (joint pain)
  7. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  8. Breast cancer
  9. Breast discharge
  10. Breast hyperplasia (accumulation of abnormal cells in a breast duct)

40-49:

  1. Diarrhoea
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
  4. Stomatitis (inflammation of mucous membrane of mouth)
  5. Urine output decreased
  6. Decreased appetite
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Fall
  9. Haemoglobin decreased
  10. Multiple myeloma (cancer of the plasma cells)

50-59:

  1. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  2. Arthralgia (joint pain)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Decreased appetite
  5. Deformity (disfigurement)
  6. Depression
  7. Dysaesthesia (abnormal sensation)
  8. Fatigue (feeling of tiredness)
  9. Gastric ulcer (stomach ulcer)
  10. Herpes zoster

60+:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Anxiety
  3. Epistaxis (bleed from the nose)
  4. Mouth haemorrhage (bleeding from mouth)
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Asthenia (weakness)
  7. Dyspnoea (difficult or laboured respiration)
  8. Confusional state
  9. Dehydration (dryness resulting from the removal of water)
  10. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 20 people, 35.09%
  2. Immunodeficiency Disorders: 14 people, 24.56%
  3. Osteoporosis (bones weak and more likely to break): 4 people, 7.02%
  4. Indigestion: 4 people, 7.02%
  5. Fever: 4 people, 7.02%
  6. Anaemia (lack of blood): 4 people, 7.02%
  7. Nausea (feeling of having an urge to vomit): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Magnesium and Alkeran?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Magnesium and Alkeran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alkeran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alkeran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on magnesium and melphalan (the active ingredients of Magnesium and Alkeran, respectively), and Magnesium and Alkeran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: