Magnesium and Lorbrena drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Magnesium (magnesium) and Lorbrena (lorlatinib). Common drug interactions include delirium among females and nervous system disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Magnesium and Lorbrena. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,145 Magnesium users. Check the latest studies of Magnesium.

What is Lorbrena?

Lorbrena has active ingredients of lorlatinib. eHealthMe is studying from 2,148 Lorbrena users. Check the latest studies of Lorbrena.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

22 people who take Magnesium and Lorbrena together, and have interactions are studied.

Magnesium and Lorbrena drug interactions.

What are the common drug interactions of Magnesium and Lorbrena, by gender? *:

female:

Delirium (wild excitement)
Hallucination (an experience involving the perception of something not present)
Neoplasm progression (growth of tumour)
Hallucination, visual (seeing things that aren't there)
Low density lipoprotein increased (cholesterol increased in blood)
Soliloquy
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Blood cholesterol increased
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)

male:

Nervous system disorder (a general class of medical conditions affecting the nervous system)
Anger
Blood alkaline phosphatase increased
Blood triglycerides increased
Drug intolerance (drug sensitivity)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Headache (pain in head)

What are the common drug interactions of Magnesium and Lorbrena, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)

40-49:

Headache (pain in head)
Renal impairment (severely reduced kidney function)
Completed suicide (act of taking one's own life)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Pneumatosis intestinalis (air or gas in an intestine)
Small intestinal perforation (hole in small intestine)

50-59:

Anger
Eosinophil percentage increased
Fall
Head injury
Loss of consciousness
Monocyte percentage increased
Nervous system disorder (a general class of medical conditions affecting the nervous system)
White blood cell count increased
Death

60+:

Neoplasm progression (growth of tumour)
Hallucination (an experience involving the perception of something not present)
Pruritus (severe itching of the skin)
Cardiac failure acute
Death
Tremor (trembling or shaking movements in one or more parts of your body)
Blood alkaline phosphatase increased
Blood triglycerides increased
Drug intolerance (drug sensitivity)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 13 people, 59.09%
Lung Neoplasm Malignant (cancer tumour of lung): 6 people, 27.27%
Insomnia (sleeplessness): 4 people, 18.18%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
Hyperkalemia (damage to or disease of the kidney): 3 people, 13.64%
Cancer Pain: 3 people, 13.64%
Muscle Spasms (muscle contraction): 3 people, 13.64%
Nausea (feeling of having an urge to vomit): 3 people, 13.64%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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