Magnesium and Microzide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Magnesium (magnesium) and Microzide (hydrochlorothiazide). Common drug interactions include cerebrovascular accident among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Magnesium and Microzide. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,147 Magnesium users. Check the latest studies of Magnesium.

What is Microzide?

Microzide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 994 Microzide users. Check the latest studies of Microzide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

33 people who take Magnesium and Microzide together, and have interactions are studied.

Magnesium and Microzide drug interactions.

What are the common drug interactions of Magnesium and Microzide, by gender? *:

female:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fall
Hip fracture
Mood swings (an extreme or rapid change in mood)
Pain
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Abdominal strangulated hernia (abdominal blood supply damaged hernia)
Blood glucose decreased
Chronic kidney disease
Fatigue (feeling of tiredness)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Abdominal pain
Bone pain
Coagulopathy (blood's ability to clot is impaired)
Death
Diarrhoea
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pruritus (severe itching of the skin)
Vomiting

What are the common drug interactions of Magnesium and Microzide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal strangulated hernia (abdominal blood supply damaged hernia)

50-59:

Abasia (inability to walk)
Anger
Asthenia (weakness)
Blood pressure diastolic decreased
Blood pressure systolic increased
Gastric ulcer (stomach ulcer)
Haematoma (collection of blood outside the blood vessels)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Limb injury
Muscle spasms (muscle contraction)

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anxiety
Pain
Abdominal pain
Back disorder
Blood cholesterol increased
Bone pain
Breast disorder female
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Coagulopathy (blood's ability to clot is impaired)

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 7 people, 21.21%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 21.21%
Joint Pain: 6 people, 18.18%
Stress And Anxiety: 5 people, 15.15%
Back Pain: 4 people, 12.12%
Pain: 4 people, 12.12%
Neuralgia (pain in one or more nerves): 4 people, 12.12%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 12.12%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 9.09%
Neuropathy Peripheral (surface nerve damage): 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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