Makena and Asa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Makena (hydroxyprogesterone caproate) and Asa (aspirin). Common drug interactions include premature delivery among females.

The phase IV clinical study analyzes what interactions people have when they take Makena and Asa. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Makena?

Makena has active ingredients of hydroxyprogesterone caproate. eHealthMe is studying from 24,292 Makena users. Check the latest studies of Makena.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

On Jul, 14, 2026

48 people who take Makena and Asa together, and have interactions are studied.

What are the common drug interactions of Makena and Asa, by gender? *:

female:

Premature delivery
Premature labour
Induced labour (prematurely stimulating childbirth in a woman)
Injection site bruising
Labour induction
Nausea (feeling of having an urge to vomit)
Injection site swelling
Abdominal pain lower
Abdominal pain upper
Amniotic cavity infection

male:

n/a

What are the common drug interactions of Makena and Asa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Premature delivery
Abdominal pain lower
Diarrhoea

20-29:

Premature delivery
Abdominal pain upper
Amniotic cavity infection
Anaemia (lack of blood)
Dyspepsia (indigestion)
Gestational hypertension (elevated blood pressure during pregnancy)
Induced labour (prematurely stimulating childbirth in a woman)
Injection site bruising
Injection site pain
Injection site pruritus (severe itching at injection site)

30-39:

Premature delivery
Injection site pain
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Injection site erythema (redness at injection site)
Urticaria (rash of round, red welts on the skin that itch intensely)
Headache (pain in head)
Injection site pruritus (severe itching at injection site)
Injection site swelling
Back pain
Dizziness

40-49:

Premature delivery
Premature labour
Premature separation of placenta
Uterine rupture
Asthenia (weakness)
Depression
Dry skin
Emotional disorder
Nausea (feeling of having an urge to vomit)
Urine output decreased

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Premature Delivery: 42 people, 87.50%
Birth Control: 20 people, 41.67%
High Blood Pressure: 9 people, 18.75%
Nausea (feeling of having an urge to vomit): 5 people, 10.42%
Pre-Eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman): 4 people, 8.33%
Premature Labor: 3 people, 6.25%
High Risk Pregnancy: 3 people, 6.25%
Asthma: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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