Profen and Troponin i increased - a phase IV clinical study of FDA data

Summary:

Troponin i increased is reported as a side effect among people who take Profen (ibuprofen), especially for people who are female, 10-19 old, have been taking the drug for 1 - 2 years also take Paracetamol, and have Cardio-respiratory arrest.

The phase IV clinical study analyzes which people have Troponin i increased when taking Profen. It is created by eHealthMe based on reports of 239,319 people who have side effects when taking Profen from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Troponin i increased?

Troponin i increased is found to be associated with 262 drugs and 479 conditions by eHealthMe. Check the latest studies of Troponin i increased.



On Jul, 14, 2026

239,319 people reported to have side effects when taking Profen.
Among them, 29 people (0.01%) have Troponin i increased.

Could Profen cause Troponin i increased?

Among these 29 people:

How long have people been on Profen when they have Troponin i increased? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Troponin i increased when taking Profen? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Troponin i increased when taking Profen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 52 %
  • 20-29: 8 %
  • 30-39: 4 %
  • 40-49: 4 %
  • 50-59: 12 %
  • 60+: 20 %

What are other drugs people take besides Profen? *

  1. Paracetamol: 6 people, 20.69%
  2. Acetaminophen: 5 people, 17.24%
  3. Atropine: 3 people, 10.34%
  4. Midazolam: 3 people, 10.34%
  5. Compazine: 2 people, 6.90%
  6. Dexamethasone: 2 people, 6.90%
  7. Epinephrine: 2 people, 6.90%
  8. Phenytoin: 2 people, 6.90%
  9. Norco: 2 people, 6.90%
  10. Sodium Bicarbonate: 2 people, 6.90%

What are other side effects people have besides Troponin i increased? *

  1. Bradycardia (abnormally slow heart action): 16 people, 55.17%
  2. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 16 people, 55.17%
  3. Alanine Aminotransferase Increased: 15 people, 51.72%
  4. Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 14 people, 48.28%
  5. Haemodynamic Instability (disturbances in the blood movement in our body): 14 people, 48.28%
  6. Diastolic Dysfunction: 14 people, 48.28%
  7. Cardiac Arrest: 14 people, 48.28%
  8. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 14 people, 48.28%
  9. Partial Seizures (seizures which affect only a part of the brain at onset): 14 people, 48.28%
  10. Poor Peripheral Circulation: 14 people, 48.28%

What are the existing conditions these people have? *

  1. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 14 people, 48.28%
  2. Haemodynamic Instability (disturbances in the blood movement in our body): 11 people, 37.93%
  3. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 11 people, 37.93%
  4. Cardiac Arrest: 10 people, 34.48%
  5. Heart Disease: 9 people, 31.03%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 24.14%
  7. Poisoning Deliberate: 4 people, 13.79%
  8. Partial Seizures (seizures which affect only a part of the brain at onset): 4 people, 13.79%
  9. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 6.90%
  10. Enlarged Prostate: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Troponin i increased?

- Check whether Troponin i increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Profen:

Troponin i increased treatments and more:

How severe was Troponin i increased and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Troponin i increased:

Browse all the conditions that are associated with Troponin i increased:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: