Malic acid and Probiotic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Malic acid (alpha hydroxy acids) and Probiotic (bacillus coagulans). Common drug interactions include abdominal rigidity among females and abnormal dreams among males.

The phase IV clinical study analyzes what interactions people have when they take Malic acid and Probiotic. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Malic acid?

Malic acid has active ingredients of alpha hydroxy acids. It is often used in fibromyalgia. eHealthMe is studying from 246 Malic acid users. Check the latest studies of Malic acid.

What is Probiotic?

Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,461 Probiotic users. Check the latest studies of Probiotic.

On Jul, 26, 2026

15 people who take Malic acid and Probiotic together, and have interactions are studied.

Malic acid and Probiotic drug interactions.

What are the common drug interactions of Malic Acid and Probiotic, by gender? *:

female:

Abdominal rigidity
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Flatulence (flatus expelled through the anus)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Abdominal pain
Abnormal loss of weight
Alopecia (absence of hair from areas of the body)
Anxiety

male:

Abnormal dreams
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Peptic ulcer
Rash
Restlessness (not able to rest)

What are the common drug interactions of Malic Acid and Probiotic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug dependence
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

30-39:

n/a

40-49:

n/a

50-59:

Abdominal discomfort
Abdominal distension
Abdominal rigidity
Flatulence (flatus expelled through the anus)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Nausea (feeling of having an urge to vomit)

60+:

Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Eye disorder
Fatigue (feeling of tiredness)
Fear
Gait disturbance
Gastric haemorrhage (bleeding stomach)
Heart rate decreased
Hyperhidrosis (abnormally increased sweating)
Hypersomnia (excessive daytime sleepiness (eds))

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 40.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 20.00%
Drowsiness: 3 people, 20.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 20.00%
Pain: 2 people, 13.33%
Memory Loss: 2 people, 13.33%
Vision Blurred: 1 person, 6.67%
Hypertrophic Cardiomyopathy (a condition in which the heart muscle becomes abnormally thick): 1 person, 6.67%
Bladder Disorder: 1 person, 6.67%
Diarrhea: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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