Marinol and Keflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Marinol (dronabinol) and Keflex (cephalexin). Common drug interactions include mouth haemorrhage among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Marinol and Keflex. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Marinol?

Marinol has active ingredients of dronabinol. It is often used in pain. eHealthMe is studying from 4,963 Marinol users. Check the latest studies of Marinol.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.



On Aug, 02, 2026

81 people who take Marinol and Keflex together, and have interactions are studied.

Marinol and Keflex drug interactions.

What are the common drug interactions of Marinol and Keflex, by gender? *:

female:

  1. Mouth haemorrhage (bleeding from mouth)
  2. Osteonecrosis of jaw (death of bone of jaw)
  3. Pain in jaw
  4. Metastases to central nervous system (cancer spreads to central nervous system)
  5. Bone density decreased
  6. Depression
  7. Tooth extraction
  8. Abdominal pain
  9. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  10. Dysphagia (a condition in which swallowing is difficult or painful)

male:

  1. Chest pain
  2. Renal failure (kidney dysfunction)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Generalised oedema (swelling all over the body)
  5. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  6. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  7. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  8. Oropharyngeal pain
  9. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  10. Abdominal pain

What are the common drug interactions of Marinol and Keflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abnormal dreams
  2. Aphasia (damage to the parts of the brain that control language)
  3. Breast tenderness
  4. Completed suicide (act of taking one's own life)
  5. Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
  6. Disease progression
  7. Dry eye (lack of adequate tears)
  8. Fatigue (feeling of tiredness)
  9. Folliculitis (infection of hair root)
  10. Gait disturbance

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Ankle fracture
  3. Bone density decreased
  4. Depression
  5. Emotional distress
  6. Foot fracture
  7. Gait disturbance
  8. Haematochezia (passage of stools containing blood)
  9. Hand fracture
  10. Muscle atrophy (a decrease in the mass of the muscle)

30-39:

  1. Abdominal pain upper
  2. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  3. Adjustment disorder
  4. Alopecia (absence of hair from areas of the body)
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Arthralgia (joint pain)
  7. Asthma
  8. Axillary pain
  9. Back pain
  10. Balance disorder

40-49:

  1. Constipation
  2. Bone disorder
  3. Chest pain
  4. Dysuria (painful or difficult urination)
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Back pain
  7. Decreased appetite
  8. Gingival infection (gum infection)
  9. Inflammation
  10. Anaemia (lack of blood)

50-59:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Generalised oedema (swelling all over the body)
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  6. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  7. Oropharyngeal pain
  8. Abdominal pain
  9. Anaemia of chronic disease
  10. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

60+:

  1. Anaemia (lack of blood)
  2. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  3. Decreased appetite
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Deformity (disfigurement)
  6. Dementia (madness)
  7. Depression
  8. Fall
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the existing conditions these people have? *

  1. Breast Cancer Metastatic: 32 people, 39.51%
  2. Irritable Bowel Syndrome: 24 people, 29.63%
  3. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 16 people, 19.75%
  4. Breast Cancer: 12 people, 14.81%
  5. Nausea (feeling of having an urge to vomit): 11 people, 13.58%
  6. Metastases To Bone (cancer spreads to bone): 11 people, 13.58%
  7. Urinary Tract Infection: 8 people, 9.88%
  8. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 7 people, 8.64%
  9. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 5 people, 6.17%
  10. Insomnia (sleeplessness): 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

Do you take Marinol and Keflex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Marinol and Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Marinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Marinol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Keflex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dronabinol and cephalexin (the active ingredients of Marinol and Keflex, respectively), and Marinol and Keflex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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