Matulane and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Matulane (procarbazine hydrochloride) and Colace (docusate ). Common drug interactions include cerebral haemorrhage among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Matulane and Colace. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Matulane?

Matulane has active ingredients of procarbazine hydrochloride. eHealthMe is studying from 3,440 Matulane users. Check the latest studies of Matulane.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 26, 2026

47 people who take Matulane and Colace together, and have interactions are studied.

What are the common drug interactions of Matulane and Colace, by gender? *:

female:

Cerebral haemorrhage (bleeding within the brain)
Fall
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Platelet count decreased
Abdominal pain
Decreased appetite
Diarrhoea
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Lip swelling

male:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Neutropenia (an abnormally low number of neutrophils)
Vision blurred
Back pain
Drug ineffective
Dry throat
Gait disturbance
Insomnia (sleeplessness)

What are the common drug interactions of Matulane and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Platelet count decreased
White blood cell count decreased

10-19:

Alopecia (absence of hair from areas of the body)
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Vision blurred

20-29:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Overdose

30-39:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pain

40-49:

Rash generalised (rash on most of body parts)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

Fatigue (feeling of tiredness)
Abdominal pain
Decreased appetite
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Platelet count decreased
White blood cell count decreased

60+:

Cerebral haemorrhage (bleeding within the brain)
Fall
Platelet count decreased
Death
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Neutropenia (an abnormally low number of neutrophils)
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Drug ineffective

What are the existing conditions these people have? *

Brain Neoplasm Malignant (brain cancer tumour): 22 people, 46.81%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 12 people, 25.53%
Hodgkin's Lymphoma (cancer originating from white blood cells): 6 people, 12.77%

* Approximation only. Some reports may have incomplete information.

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