Matulane and Miralax drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Matulane (procarbazine hydrochloride) and Miralax (polyethylene glycol 3350). Common drug interactions include fatigue among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Matulane and Miralax. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Matulane?
Matulane has active ingredients of procarbazine hydrochloride. eHealthMe is studying from 3,440 Matulane users. Check the latest studies of Matulane.
What is Miralax?
Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.
44 people who take Matulane and Miralax together, and have interactions are studied.

What are the common drug interactions of Matulane and Miralax, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Headache (pain in head)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Vomiting
- Alopecia (absence of hair from areas of the body)
- Body temperature increased
- Contusion (a type of hematoma of tissue in which capillaries)
- Diarrhoea
- Gastric disorder (disease of stomach)
male:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Abdominal pain upper
- Adverse event
- Arthralgia (joint pain)
- Back pain
- Dyspepsia (indigestion)
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Nail discolouration (change in nail colour)
What are the common drug interactions of Matulane and Miralax, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Platelet count decreased
- White blood cell count decreased
10-19:
- Vomiting
- Alopecia (absence of hair from areas of the body)
- Hypoaesthesia (reduced sense of touch or sensation)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Vision blurred
- Back pain
- Decreased appetite
- Dyspepsia (indigestion)
- Nausea (feeling of having an urge to vomit)
- Weight decreased
20-29:
n/a
30-39:
n/a
40-49:
- Rash generalised (rash on most of body parts)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
50-59:
- Neuropathy peripheral (surface nerve damage)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Adverse event
- Diarrhoea
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
60+:
- Fatigue (feeling of tiredness)
- Decreased appetite
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Platelet disorder
- Red blood cell count decreased
What are the existing conditions these people have? *
- Brain Neoplasm Malignant (brain cancer tumour): 19 people, 43.18%
- Hodgkin's Lymphoma (cancer originating from white blood cells): 8 people, 18.18%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 9.09%
- Brain Neoplasm Benign (non-cancerous tumour of brain): 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Matulane and Miralax?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Matulane and Miralax:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Matulane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Miralax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Matulane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Miralax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on procarbazine hydrochloride and polyethylene glycol 3350 (the active ingredients of Matulane and Miralax, respectively), and Matulane and Miralax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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