Metaxalone and Lys drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metaxalone (metaxalone) and Lys (lysine). Common drug interactions include constipation among females and aortic aneurysm among males.

The phase IV clinical study analyzes what interactions people have when they take Metaxalone and Lys. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

What is Lys?

Lys has active ingredients of lysine. eHealthMe is studying from 16,532 Lys users. Check the latest studies of Lys.

On Jul, 18, 2026

24 people who take Metaxalone and Lys together, and have interactions are studied.

What are the common drug interactions of Metaxalone and Lys, by gender? *:

female:

Constipation
Diarrhoea
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Food craving
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Herpes virus infection
Infusion site scar
Infusion site swelling

male:

Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Behcet's syndrome (involves inflammation of the blood vessels)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tobacco abuse
Blood pressure decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis (inflammation of colon)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Intestinal polyp (small growths in the bowel with the potential for further growth)
Pulmonary mass

What are the common drug interactions of Metaxalone and Lys, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cystic fibrosis (disease of the secretary glands)

40-49:

n/a

50-59:

Behcet's syndrome (involves inflammation of the blood vessels)
Blood pressure decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis (inflammation of colon)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Intestinal polyp (small growths in the bowel with the potential for further growth)
Pulmonary mass
Renal cyst (kidney cyst)
Renal disorder (kidney disease)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

60+:

Jaundice cholestatic
Metastases to peritoneum (cancer spreads to peritoneum)
Obstruction gastric (obstruction in stomach)
Pancreatic carcinoma (pancreatic cancer)
Skin cancer
Small intestine carcinoma (cancer tumour of small intestine)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 25.00%
Cystic Fibrosis (disease of the secretary glands): 6 people, 25.00%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 5 people, 20.83%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 16.67%
Constipation: 3 people, 12.50%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 8.33%
High Blood Pressure: 2 people, 8.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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