Maxalt-mlt and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt-mlt (rizatriptan benzoate) and Clonidine (clonidine). Common drug interactions include tooth infection among females and tooth infection among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt-mlt and Clonidine. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt-mlt?

Maxalt-mlt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 1,534 Maxalt-mlt users. Check the latest studies of Maxalt-mlt.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.



On Aug, 05, 2026

35 people who take Maxalt-mlt and Clonidine together, and have interactions are studied.

Maxalt-mlt and Clonidine drug interactions.

What are the common drug interactions of Maxalt-Mlt and Clonidine, by gender? *:

female:

  1. Tooth infection
  2. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  3. Staphylococcal infection (an infection with staphylococcus bacteria)
  4. Arthropathy
  5. Bladder spasm
  6. Cystitis interstitial (unknown cause characterized by bladder pain)
  7. Depression
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Drug ineffective
  10. Drug intolerance (drug sensitivity)

male:

  1. Tooth infection

What are the common drug interactions of Maxalt-Mlt and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Constipation
  2. Drug effect prolonged
  3. Hyperhidrosis (abnormally increased sweating)
  4. Hypopnoea (decrease in the breathing rate)
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Pain
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  8. Upper-airway cough syndrome
  9. Vomiting

30-39:

n/a

40-49:

  1. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  2. Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
  3. Morton's neuroma (a nerve tumour non cancer that affects one of the nerves that run between the long bones (metatarsals) in the foot)
  4. Oesophageal spasm (contraction of oesophagus)
  5. Oscillopsia (a visual disturbance in which objects in the visual field appear to oscillate)
  6. Pain
  7. Self-injurious ideation
  8. Suicide attempt
  9. Urinary retention (the inability to completely or partially empty the bladder)
  10. Vomiting

50-59:

  1. Asthma
  2. Blood creatine phosphokinase increased
  3. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 42.86%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 22.86%
  3. Immunodeficiency Common Variable: 8 people, 22.86%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 20.00%
  5. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 8.57%
  6. Nausea And Vomiting: 3 people, 8.57%
  7. Asthma: 3 people, 8.57%
  8. Dyspnea (difficult or laboured breathing): 3 people, 8.57%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.57%
  10. Insomnia (sleeplessness): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Maxalt-mlt and Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Maxalt-mlt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxalt-mlt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on rizatriptan benzoate and clonidine (the active ingredients of Maxalt-mlt and Clonidine, respectively), and Maxalt-mlt and Clonidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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