Maxalt-mlt and Duragesic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt-mlt (rizatriptan benzoate) and Duragesic (fentanyl). Common drug interactions include sleep disorder among females and brain injury among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt-mlt and Duragesic. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt-mlt?

Maxalt-mlt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 1,534 Maxalt-mlt users. Check the latest studies of Maxalt-mlt.

What is Duragesic?

Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.

On Jul, 12, 2026

43 people who take Maxalt-mlt and Duragesic together, and have interactions are studied.

Maxalt-mlt and Duragesic drug interactions.

What are the common drug interactions of Maxalt-Mlt and Duragesic, by gender? *:

female:

Sleep disorder
Spinal osteoarthritis (joint cartilage loss in spine)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Disturbance in attention
Gallbladder polyp (growths or lesions resembling growths (polypoid lesions) in the wall of the gallbladder)
Mobility decreased (ability to move is reduced)
Stomatitis (inflammation of mucous membrane of mouth)
Surgery
Tooth extraction
Wound

male:

Brain injury
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Fall
Gun shot wound
Haemorrhage (bleeding)
Headache (pain in head)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Multi-organ disorder (multiple organ disease)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Petechiae (a small red or purple spot caused by bleeding into the skin)

What are the common drug interactions of Maxalt-Mlt and Duragesic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Brain injury
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Depression
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Paralysis
Chronic kidney disease
Epistaxis (bleed from the nose)
Headache (pain in head)

50-59:

Fall
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Nausea (feeling of having an urge to vomit)
Vomiting
Asthenia (weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Abdominal pain
Accident at work
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)

60+:

Drug ineffective
Drug hypersensitivity
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Respiratory failure (inadequate gas exchange by the respiratory system)
Urinary tract infection
Pruritus (severe itching of the skin)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Bladder dysfunction
Fall
Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the existing conditions these people have? *

Breast Cancer Metastatic: 24 people, 55.81%
Hot Flush (sudden feelings of heat): 21 people, 48.84%
Discomfort: 21 people, 48.84%
Breast Cancer: 21 people, 48.84%
Ovarian Cancer (cancer of ovary): 21 people, 48.84%
Neoplasm Malignant (cancer tumour): 21 people, 48.84%
Granulocyte Count Decreased: 20 people, 46.51%
Pain: 20 people, 46.51%
Stress And Anxiety: 14 people, 32.56%
Restless Leg Syndrome (a powerful urge to move your legs): 12 people, 27.91%

* Approximation only. Some reports may have incomplete information.

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