Mercaptopurine and Uceris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mercaptopurine (mercaptopurine) and Uceris (budesonide). Common drug interactions include drug ineffective among females and frequent bowel movements among males.

The phase IV clinical study analyzes what interactions people have when they take Mercaptopurine and Uceris. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.

What is Uceris?

Uceris has active ingredients of budesonide. It is often used in ulcerative colitis. eHealthMe is studying from 1,721 Uceris users. Check the latest studies of Uceris.

On Jul, 12, 2026

44 people who take Mercaptopurine and Uceris together, and have interactions are studied.

Mercaptopurine and Uceris drug interactions.

What are the common drug interactions of Mercaptopurine and Uceris, by gender? *:

female:

Drug ineffective
Asthenia (weakness)
Drug effect decreased
Gastric ulcer perforation (stomach hole due to ulcer)
Haematochezia (passage of stools containing blood)
Myalgia (muscle pain)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Abnormal faeces (abnormal stool)
Antinuclear antibody positive
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)

male:

Frequent bowel movements
Fatigue (feeling of tiredness)
White blood cell count decreased
Defaecation urgency (a sudden compelling urge to defecate)
Diarrhoea
Injection site erythema (redness at injection site)
Malaise (a feeling of general discomfort or uneasiness)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Cerebral haemorrhage (bleeding within the brain)
Dizziness

What are the common drug interactions of Mercaptopurine and Uceris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Device related infection
Small intestinal obstruction (blockage in small intestine)

20-29:

Acne (skin problems that cause pimples)
Fistula discharge (discharge from abnormal passage of structure/organ)
Nausea (feeling of having an urge to vomit)
Rectal abscess (pus in rectum)
Subcutaneous abscess
Vomiting
Wound haemorrhage (bleeding wound)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Asthenia (weakness)

30-39:

Frequent bowel movements
Body temperature increased
Cellulitis (infection under the skin)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Fatigue (feeling of tiredness)
Feeling hot
Haematochezia (passage of stools containing blood)
White blood cell count decreased
Acne (skin problems that cause pimples)
Nausea (feeling of having an urge to vomit)

40-49:

Urinary incontinence (inability to control the flow of urine and involuntary urination)
Abnormal faeces (abnormal stool)
Flatulence (flatus expelled through the anus)
Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
Decreased appetite
Diarrhoea
Fatigue (feeling of tiredness)
Hangover
Hypersomnia (excessive daytime sleepiness (eds))
Injection site erythema (redness at injection site)

50-59:

Gastric ulcer perforation (stomach hole due to ulcer)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Cataract (clouding of the lens inside the eye)
Drug ineffective

60+:

Drug ineffective
Defaecation urgency (a sudden compelling urge to defecate)
Pneumonia
Weight decreased
Breast cancer
Colitis (inflammation of colon)
Flatulence (flatus expelled through the anus)
Injection site pain
Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

What are the existing conditions these people have? *

Pain: 6 people, 13.64%
Nausea (feeling of having an urge to vomit): 4 people, 9.09%
Herpes Zoster: 4 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.09%
Stress And Anxiety: 3 people, 6.82%
Multiple Allergies (allergy to multiple agents): 3 people, 6.82%
Hypersensitivity: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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