Maxalt-mlt and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt-mlt (rizatriptan benzoate) and Effexor (venlafaxine hydrochloride). Common drug interactions include insomnia among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt-mlt and Effexor. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt-mlt?

Maxalt-mlt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 1,534 Maxalt-mlt users. Check the latest studies of Maxalt-mlt.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

On Jul, 30, 2026

55 people who take Maxalt-mlt and Effexor together, and have interactions are studied.

Maxalt-mlt and Effexor drug interactions.

What are the common drug interactions of Maxalt-Mlt and Effexor, by gender? *:

female:

Insomnia (sleeplessness)
Aspartate aminotransferase increased
Asthma
Blood magnesium increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic kidney disease
Crying
Depressed level of consciousness
Headache (pain in head)
Hereditary angioedema (recurrent episodes of severe swelling)

male:

Neutropenia (an abnormally low number of neutrophils)

What are the common drug interactions of Maxalt-Mlt and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Crying
Drug hypersensitivity
Hypertension (high blood pressure)
Muscle rigidity (muscle stiffness)
Muscle twitching
Nephrolithiasis (calculi in the kidneys)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Parasomnia (sleep disorders that involve abnormal and unnatural movements, behaviours, emotions, perceptions)
Sleep terror (felling of terror in sleep)

30-39:

Heart rate increased
Hypotension (abnormally low blood pressure)
Impaired gastric emptying
Nausea (feeling of having an urge to vomit)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dysarthria (speech disorder)
Headache (pain in head)
Loss of consciousness
Muscle spasms (muscle contraction)
Palpitations (feelings or sensations that your heart is pounding or racing)

40-49:

Insomnia (sleeplessness)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hunger
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Self-injurious ideation
Suicide attempt
Fatigue (feeling of tiredness)
Limb injury
Osteomyelitis (infection of bone)
Suicidal ideation

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Asthma
Hereditary angioedema (recurrent episodes of severe swelling)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Sinus disorder (disease of sinus)
Sinusitis (inflammation of sinus)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Chronic kidney disease

60+:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Cough
Ejection fraction decreased (systolic heart failure)
Heart rate irregular
Hypersensitivity
Injection site haematoma (localized swelling filled with blood at injection site)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 32 people, 58.18%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 25.45%
Asthma: 6 people, 10.91%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 9.09%
Stress And Anxiety: 5 people, 9.09%
Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 4 people, 7.27%
Hereditary Angioedema (recurrent episodes of severe swelling): 4 people, 7.27%
Blood Potassium Decreased: 4 people, 7.27%
Cluster Headache (one-sided head pain with tearing): 4 people, 7.27%
Drowsiness: 4 people, 7.27%

* Approximation only. Some reports may have incomplete information.

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