Nexium and Exomphalos - a phase IV clinical study of FDA data

Summary:

Exomphalos is reported as a side effect among people who take Nexium (esomeprazole magnesium), especially for people who are female, 60+ old, also take Acetylsalicylic Acid, and have Conjunctivitis.

The phase IV clinical study analyzes which people have Exomphalos when taking Nexium. It is created by eHealthMe based on reports of 240,870 people who have side effects when taking Nexium from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

What is Exomphalos?

Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it) is found to be associated with 89 drugs and 133 conditions by eHealthMe. Check the latest studies of Exomphalos.



On Jul, 30, 2026

240,870 people reported to have side effects when taking Nexium.
Among them, 11 people (0.0%) have Exomphalos.

Could Nexium cause Exomphalos?

Among these 11 people:

What is the gender of people who have Exomphalos when taking Nexium? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Exomphalos when taking Nexium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Nexium? *

  1. Zoloft: 10 people, 90.91%
  2. Tobrex: 10 people, 90.91%
  3. Fluconazole: 10 people, 90.91%
  4. Acetylsalicylic Acid: 10 people, 90.91%
  5. Ortho Tri-Cyclen: 9 people, 81.82%
  6. Augmentin: 6 people, 54.55%
  7. Augmentin '125': 4 people, 36.36%
  8. Azithromycin: 3 people, 27.27%
  9. Folic Acid: 3 people, 27.27%
  10. Amoxicillin: 2 people, 18.18%

What are other side effects people have besides Exomphalos? *

  1. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 10 people, 90.91%
  2. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 10 people, 90.91%
  3. Ascites (accumulation of fluid in the abdominal cavity): 10 people, 90.91%
  4. Cardiac Arrest: 10 people, 90.91%
  5. Growth Retardation (delayed growth): 10 people, 90.91%
  6. Heart Rate Decreased: 10 people, 90.91%
  7. Hepatic Vein Thrombosis (obstruction in the veins of the liver caused by a blood clot): 10 people, 90.91%
  8. Hyperglycemia (high blood sugar): 10 people, 90.91%
  9. Anaemia (lack of blood): 10 people, 90.91%
  10. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 9 people, 81.82%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 10 people, 90.91%
  2. Sinusitis (inflammation of sinus): 10 people, 90.91%
  3. Conjunctivitis (pink eye): 10 people, 90.91%
  4. Stress And Anxiety: 7 people, 63.64%
  5. Depression: 7 people, 63.64%
  6. High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and have Exomphalos?

- Check whether Exomphalos is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nexium:

Exomphalos treatments and more:

How severe was Exomphalos and when was it recovered:

Expand to all the drugs that have ingredients of esomeprazole magnesium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Exomphalos:

Browse all the conditions that are associated with Exomphalos:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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