Maxalt and Cimzia drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Maxalt (rizatriptan benzoate) and Cimzia (certolizumab pegol). Common drug interactions include pain among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Maxalt and Cimzia. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Maxalt?
Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.
What is Cimzia?
Cimzia has active ingredients of certolizumab pegol. It is often used in rheumatoid arthritis. eHealthMe is studying from 106,745 Cimzia users. Check the latest studies of Cimzia.
41 people who take Maxalt and Cimzia together, and have interactions are studied.

What are the common drug interactions of Maxalt and Cimzia, by gender? *:
female:
- Pain
- Cystitis (inflammation of the wall of the bladder)
- Injection site pain
- Injection site haemorrhage (bleeding from injection site)
- Injection site vesicles (fluid- or air-filled cavity or sac at injection site)
- Pneumonia
- Anxiety
- Depression
- Pruritus (severe itching of the skin)
- Urticaria (rash of round, red welts on the skin that itch intensely)
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Blood pressure increased
- Headache (pain in head)
- Metastatic malignant melanoma (spreadable cancer tumour of melanine)
- Agitation (state of anxiety or nervous excitement)
- Arthritis enteropathic (form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease)
- Insomnia (sleeplessness)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Substance-induced psychotic disorder
What are the common drug interactions of Maxalt and Cimzia, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Agitation (state of anxiety or nervous excitement)
- Arthritis enteropathic (form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease)
- Insomnia (sleeplessness)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Substance-induced psychotic disorder
20-29:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Deformity (disfigurement)
- Gallbladder disorder
- Injury
- Pain
- Pancreatitis (inflammation of pancreas)
- Septic shock (shock due to blood infection)
- Thrombosis (formation of a blood clot inside a blood vessel)
30-39:
- Anxiety
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Pain
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Rectal haemorrhage (bleeding from anus)
- Dehydration (dryness resulting from the removal of water)
- Depression
- Infection
- Rash macular (small, flat red spots)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
40-49:
- Vision blurred
- Visual impairment
50-59:
- Pruritus (severe itching of the skin)
- Anxiety
- Arthralgia (joint pain)
- Breast cancer
- Chest wall mass
- Cough
- Dizziness
- Dry throat
- Erythema (redness of the skin)
- Herpes simplex (herpes simplex is a common viral infection)
60+:
- Asthenia (weakness)
- Cough
- Skin nodule (slightly elevated lesions on or in the skin)
- Cystitis (inflammation of the wall of the bladder)
- Pneumonia
- Pyrexia (fever)
- Wheezing (a high-pitched whistling sound made while you breath)
- Blood glucose increased
- Blood pressure increased
- Headache (pain in head)
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 29.27%
- Stress And Anxiety: 3 people, 7.32%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.32%
- Headache (pain in head): 3 people, 7.32%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
Do you take Maxalt and Cimzia?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Maxalt and Cimzia:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Maxalt:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cimzia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxalt and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cimzia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on rizatriptan benzoate and certolizumab pegol (the active ingredients of Maxalt and Cimzia, respectively), and Maxalt and Cimzia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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