Maxalt and Solu-medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt (rizatriptan benzoate) and Solu-medrol (methylprednisolone sodium succinate). Common drug interactions include osteoarthritis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Maxalt and Solu-medrol. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

On Jul, 06, 2026

78 people who take Maxalt and Solu-medrol together, and have interactions are studied.

Maxalt and Solu-medrol drug interactions.

What are the common drug interactions of Maxalt and Solu-Medrol, by gender? *:

female:

Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in extremity
Paralysis
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Urinary tract infection
White blood cell count decreased
Drug intolerance (drug sensitivity)

male:

Fatigue (feeling of tiredness)
Abdominal discomfort
Balanitis candida (inflammation of the glands penis by infection with candida albicans)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cerebellar infarction (impaired blood circulation to cerebellum)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
Cerebral artery stenosis (hardening of brain blood vessels)
Cerebral ventricle dilatation (enlargement of ventricle of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Maxalt and Solu-Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal discomfort
Anxiety
Asthenia (weakness)
Blindness unilateral
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Ear infection
Emotional distress
Eye infection
Eye irritation
Eye pain

20-29:

n/a

30-39:

Nausea (feeling of having an urge to vomit)
Pain
Vomiting
Arthralgia (joint pain)
Balance disorder
Diarrhoea
Fatigue (feeling of tiredness)
Injury
Insomnia (sleeplessness)
Oropharyngeal pain

40-49:

Pneumonia
Drug intolerance (drug sensitivity)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
Neutropenia (an abnormally low number of neutrophils)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Red blood cell sedimentation rate increased
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
White blood cell count decreased
Dyspnoea (difficult or laboured respiration)

50-59:

Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Ataxia (loss of full control of bodily movements)
Atelectasis (partial or complete collapse of the lung)
B-lymphocyte count decreased
Back pain
Balanitis candida (inflammation of the glands penis by infection with candida albicans)
Blood immunoglobulin a decreased
Breast abscess
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Pneumonia
Fall
Dry eye (lack of adequate tears)
Head injury
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Injury corneal
Limb injury
Menstrual disorder (disease of menstrual cycle)
Mitral valve incompetence (inefficient heart valve)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 8.97%
Headache (pain in head): 6 people, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 6.41%
Optic Neuritis (optic nerve inflammation): 5 people, 6.41%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 6.41%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 5.13%
Nausea (feeling of having an urge to vomit): 4 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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