Maxalt and Sprintec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxalt (rizatriptan benzoate) and Sprintec (ethinyl estradiol; norgestimate). Common drug interactions include cough among females.

The phase IV clinical study analyzes what interactions people have when they take Maxalt and Sprintec. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

On Jul, 07, 2026

19 people who take Maxalt and Sprintec together, and have interactions are studied.

What are the common drug interactions of Maxalt and Sprintec, by gender? *:

female:

Cough
Headache (pain in head)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Balance disorder
Biliary colic
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Chest pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

n/a

What are the common drug interactions of Maxalt and Sprintec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dizziness
Nausea (feeling of having an urge to vomit)

20-29:

Abortion spontaneous (naturally occurring miscarriage)
Biliary colic
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Emotional distress
Injury
Nausea (feeling of having an urge to vomit)
Pain
Pyrexia (fever)

30-39:

Headache (pain in head)

40-49:

Anaemia (lack of blood)
Epicondylitis (tennis elbow)
Gastritis (inflammation of stomach)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
General physical health deterioration (weak health status)
Hepatic enzyme increased
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypersomnia (excessive daytime sleepiness (eds))
Hypertension (high blood pressure)

50-59:

Headache (pain in head)

60+:

n/a

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 26.32%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 26.32%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.79%
Drowsiness: 3 people, 15.79%
Hypersensitivity: 2 people, 10.53%
Food Allergy: 2 people, 10.53%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 5.26%
Constipation: 1 person, 5.26%
Dizziness: 1 person, 5.26%
Gastric Ulcer (stomach ulcer): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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