Maxipime and Gentamicin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Maxipime (cefepime hydrochloride) and Gentamicin (gentamicin sulfate). Common drug interactions include rectal haemorrhage among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Maxipime and Gentamicin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.
What is Maxipime?
Maxipime has active ingredients of cefepime hydrochloride. eHealthMe is studying from 4,279 Maxipime users. Check the latest studies of Maxipime.
What is Gentamicin?
Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.
77 people who take Maxipime and Gentamicin together, and have interactions are studied.

What are the common drug interactions of Maxipime and Gentamicin, by gender? *:
female:
- Rectal haemorrhage (bleeding from anus)
- Streptococcal infection
- Swelling
- Synovial cyst (cyst of joint filled with synovial fluid)
- Tenderness (pain or discomfort when an affected area is touched)
- Venous insufficiency (poor circulation of blood caused by damaged or enlarged veins)
- Weight decreased
- Arthropathy
- Compression fracture (fracture due to pressure caused by injury)
- Fall
male:
- Renal failure (kidney dysfunction)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Dermal cyst
- Duodenal ulcer
- Encephalitis viral (inflammation of the brain due to viral infection)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Insomnia (sleeplessness)
- Neutropenia (an abnormally low number of neutrophils)
- Papule
- Patella fracture
What are the common drug interactions of Maxipime and Gentamicin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Ataxia (loss of full control of bodily movements)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Septic shock (shock due to blood infection)
- Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
- Alanine aminotransferase increased
- Cardiac failure
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Diarrhoea
10-19:
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Renal failure (kidney dysfunction)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Nephropathy toxic (damage to kidney due to toxins)
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Leukoencephalopathy (disease of the white matter in the brain)
- Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
- Renal tubular necrosis (death of kidney tubules)
- Brain death
- Cerebral ventricle dilatation (enlargement of ventricle of brain)
20-29:
n/a
30-39:
- Cardiac arrest
- Concomitant disease progression (progress in accompanying disease)
- General physical health deterioration (weak health status)
- Pulmonary oedema (fluid accumulation in the lungs)
- Renal failure (kidney dysfunction)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
40-49:
n/a
50-59:
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Insomnia (sleeplessness)
- Neutropenia (an abnormally low number of neutrophils)
- Papule
- Patella fracture
- Pulmonary artery thrombosis (blockage of the main artery of the lung)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
- Substance-induced psychotic disorder
- Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
60+:
- Anaemia (lack of blood)
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Device failure
- Device related infection
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gingival oedema (swelling of gums)
- Haematochezia (passage of stools containing blood)
- Hypercoagulation (increased tendency for clotting of the blood)
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 18 people, 23.38%
- Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 13 people, 16.88%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 5.19%
* Approximation only. Some reports may have incomplete information.
Do you take Maxipime and Gentamicin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Maxipime (4,279 reports)
- Gentamicin (21,654 reports)
Browse all drug interactions of Maxipime and Gentamicin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Maxipime:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gentamicin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxipime and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gentamicin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cefepime hydrochloride and gentamicin sulfate (the active ingredients of Maxipime and Gentamicin, respectively), and Maxipime and Gentamicin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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