Maxzide and Fluconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Fluconazole (fluconazole). Common drug interactions include respiratory failure among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Fluconazole. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

On Jul, 15, 2026

47 people who take Maxzide and Fluconazole together, and have interactions are studied.

Maxzide and Fluconazole drug interactions.

What are the common drug interactions of Maxzide and Fluconazole, by gender? *:

female:

Respiratory failure (inadequate gas exchange by the respiratory system)
Suicidal ideation
Syncope (loss of consciousness with an inability to maintain postural tone)
Tinnitus (a ringing in the ears)
Tremor (trembling or shaking movements in one or more parts of your body)
Tricuspid valve incompetence (inefficient heart valve)
Upper respiratory tract infection
Weight decreased
Weight increased
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)

male:

Alanine aminotransferase increased
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Cardiac failure congestive
Cushingoid (obesity and weakening of the muscles)
Fat tissue increased
Hypercholesterolaemia (high levels of cholesterol in the blood)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Atherosclerosis (disorder of the arteries)

What are the common drug interactions of Maxzide and Fluconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Depression
Chronic kidney disease
Cough
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)

50-59:

Cushingoid (obesity and weakening of the muscles)
Fat tissue increased
Hypercholesterolaemia (high levels of cholesterol in the blood)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal failure (kidney dysfunction)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Atherosclerosis (disorder of the arteries)
Blood cholesterol increased

60+:

Pneumonia
Vomiting
Neutropenia (an abnormally low number of neutrophils)
Renal failure (kidney dysfunction)
Urinary tract infection
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Bacteraemia (presence of bacteria in the blood)
Carotid artery stenosis (narrowing of carotid artery)
Cellulitis (infection under the skin)

What are the existing conditions these people have? *

Pain: 7 people, 14.89%
High Blood Cholesterol: 7 people, 14.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.77%
Depression: 6 people, 12.77%
Infection: 4 people, 8.51%
Fungal Infection: 4 people, 8.51%
Stress And Anxiety: 3 people, 6.38%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.38%
Indigestion: 3 people, 6.38%
Hypersensitivity: 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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