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Naproxen sodium and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen sodium (naproxen sodium) and Lanoxin (digoxin). Common drug interactions include hypertension among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen sodium and Lanoxin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen sodium?

Naproxen sodium has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 11,252 Naproxen sodium users. Check the latest studies of Naproxen sodium.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

On Jul, 15, 2026

12 people who take Naproxen sodium and Lanoxin together, and have interactions are studied.

Naproxen sodium and Lanoxin drug interactions.

What are the common drug interactions of Naproxen Sodium and Lanoxin, by gender? *:

female:

  1. Hypertension (high blood pressure)

male:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Blood bilirubin increased
  3. Chest pain
  4. Disease progression
  5. Dyspnoea (difficult or laboured respiration)
  6. Haematocrit decreased
  7. Abdominal pain
  8. Anaemia (lack of blood)
  9. Bloody peritoneal effluent
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Naproxen Sodium and Lanoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood bilirubin increased
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Oedema (fluid collection in tissue)
  4. Blood pressure decreased
  5. Haemoglobin decreased
  6. Fatigue (feeling of tiredness)
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Cardiac arrest
  9. Disease progression
  10. Dyspnoea (difficult or laboured respiration)

40-49:

n/a

50-59:

n/a

60+:

  1. Cardiac disorder
  2. Chest pain
  3. Haemoglobin decreased
  4. Hypertension (high blood pressure)
  5. Nausea (feeling of having an urge to vomit)
  6. Occult blood positive
  7. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Vomiting
  10. Abdominal pain

What are the existing conditions these people have? *

  1. Thrombocytopenia (decrease of platelets in blood): 1 person, 8.33%
  2. Ear Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen sodium and Lanoxin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naproxen sodium and Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naproxen sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naproxen sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium and digoxin (the active ingredients of Naproxen sodium and Lanoxin, respectively), and Naproxen sodium and Lanoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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