Maxzide and Nabumetone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Nabumetone (nabumetone). Common drug interactions include injury among females and abscess limb among males.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Nabumetone. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Nabumetone?

Nabumetone has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 9,554 Nabumetone users. Check the latest studies of Nabumetone.

On Jul, 30, 2026

16 people who take Maxzide and Nabumetone together, and have interactions are studied.

Maxzide and Nabumetone drug interactions.

What are the common drug interactions of Maxzide and Nabumetone, by gender? *:

female:

Injury
Intervertebral disc degeneration (spinal disc degeneration)
Joint crepitation
Labyrinthitis (inflammation of the labyrinth or inner ear)
Lethargy (tiredness)
Lower respiratory tract infection
Memory impairment
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Mitral valve incompetence (inefficient heart valve)
Muscular weakness (muscle weakness)

male:

Abscess limb (limb infection)
Cellulitis (infection under the skin)
Drug ineffective
Haemodialysis-induced symptom
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Multi-organ failure (multisystem organ failure)
Pain in extremity
Peritoneal haemorrhage (peritoneal bleeding)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Maxzide and Nabumetone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Benign hepatic neoplasm (benign (non-cancerous) tumours of the liver)
Cerebral haemorrhage (bleeding within the brain)
Cerebral thrombosis (blood clot in brain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Embolism arterial (blood clot that has travelled through your arteries and become stuck)
Gallbladder disorder
Hepatic adenoma (benign liver tumour)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

Muscular weakness (muscle weakness)
Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)

60+:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Skin discolouration (change of skin colour)
Arthralgia (joint pain)
Atrioventricular block second degree (heart block second degree)
Back pain
Blood albumin increased
Blood creatinine increased
Blood glucose increased
Blood urea increased
Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

Hypotension (abnormally low blood pressure): 3 people, 18.75%
Weight Decreased: 2 people, 12.50%
Constipation: 2 people, 12.50%
Osteoporosis (bones weak and more likely to break): 2 people, 12.50%
Depression: 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 12.50%
High Blood Cholesterol: 2 people, 12.50%
Type 2 Diabetes: 2 people, 12.50%
Migraine (headache): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Maxzide and Nabumetone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously