Maxzide and Rezulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Rezulin (troglitazone). Common drug interactions include blood glucose increased among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Maxzide and Rezulin. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

What is Rezulin?

Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.

On Jul, 12, 2026

66 people who take Maxzide and Rezulin together, and have interactions are studied.

What are the common drug interactions of Maxzide and Rezulin, by gender? *:

female:

Blood glucose increased
Budd chiari syndrome (problem that results from blood clotting in the veins flowing out of the liver (hepatic veins))
Chest pain
Cholecystitis (infection of gallbladder)
Depression
Gastritis (inflammation of stomach)
Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glycosylated haemoglobin increased
Haematuria present (presence of blood in urine due to trauma)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

male:

Back pain
Nausea (feeling of having an urge to vomit)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hypersensitivity
Insomnia (sleeplessness)
Irritability
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Malaise (a feeling of general discomfort or uneasiness)
Metastases to liver (cancer spreads to liver)

What are the common drug interactions of Maxzide and Rezulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Liver fatty (fat deposition of liver)
Vaginal candidiasis (vaginal fungal infection)
Inflammation
Weight increased
Abdominal pain
Chest pain
Constipation
Depression
Diarrhoea

40-49:

Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatic fibrosis (scarring process that represents the liver's response to injury)
Haemoglobin decreased
Malaise (a feeling of general discomfort or uneasiness)
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatitis (inflammation of the liver)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

50-59:

Back pain
Cardiac failure congestive
Completed suicide (act of taking one's own life)
Duodenal ulcer
Face oedema (swelling of face)
Faeces discoloured
Flatulence (flatus expelled through the anus)
Gamma-glutamyltransferase increased
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hepatic necrosis (large portions of liver die off due to severe liver disease)

60+:

Hepatic failure (liver failure)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Aspartate aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Facial palsy (paralysis of face nerve)
Hemiparesis (weakness on one side of the body)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Renal failure acute (rapid kidney dysfunction)
Rib fracture
Spondylosis (a defect of a vertebra)

* Approximation only. Some reports may have incomplete information.

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