Megace and Zyvox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megace (megestrol acetate) and Zyvox (linezolid). Common drug interactions include back pain among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Megace and Zyvox. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

On Aug, 11, 2026

67 people who take Megace and Zyvox together, and have interactions are studied.

What are the common drug interactions of Megace and Zyvox, by gender? *:

female:

Back pain
Bone disorder
Thrombocytopenia (decrease of platelets in blood)
Pain
Pneumonia
Pleural effusion (water on the lungs)
Osteomyelitis (infection of bone)
Spinal osteoarthritis (joint cartilage loss in spine)
Blood creatinine increased
Nausea (feeling of having an urge to vomit)

male:

Pneumonia
Back pain
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Splenomegaly (enlargement of spleen)
Aeromona infection (infection caused by bacteria aeromona)
Anaemia (lack of blood)
Aortic valve incompetence
Arteriovenous fistula occlusion
Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Megace and Zyvox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Urinary tract infection
Anaemia (lack of blood)
Asthenia (weakness)
Back pain
Bone disorder
Cardiac failure congestive
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Dizziness
Hyperkalaemia (damage to or disease of the kidney)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))

50-59:

International normalised ratio increased
Haemorrhage (bleeding)
Tuberculosis (a bacterial infection by mycobacterium tuberculosis)

60+:

Pneumonia
Back pain
Blood creatinine increased
Oedema peripheral (superficial swelling)
Osteonecrosis of jaw (death of bone of jaw)
Atelectasis (partial or complete collapse of the lung)
Dysphagia (a condition in which swallowing is difficult or painful)
Nausea (feeling of having an urge to vomit)
Confusional state
Diarrhoea

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 10.45%
Multiple Myeloma (cancer of the plasma cells): 6 people, 8.96%
Infection: 4 people, 5.97%
Bone Disorder: 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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