Estradiol and Affect lability - a phase IV clinical study of FDA data

Summary:

Affect lability is reported as a side effect among people who take Estradiol (estradiol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lisinopril, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Affect lability when taking Estradiol. It is created by eHealthMe based on reports of 17,352 people who have side effects when taking Estradiol from the FDA, and is updated regularly.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

What is Affect lability?

Affect lability (emotional incontinence) is found to be associated with 667 drugs and 830 conditions by eHealthMe. Check the latest studies of Affect lability.

On Aug, 11, 2026

17,352 people reported to have side effects when taking Estradiol.
Among them, 14 people (0.08%) have Affect lability.

Among these 14 people:

How long have people been on Estradiol when they have Affect lability? *

What is the gender of people who have Affect lability when taking Estradiol? *

female: 100 %
male: 0.0 %

What is the age of people who have Affect lability when taking Estradiol? *

What are other drugs people take besides Estradiol? *

What are other side effects people have besides Affect lability? *

Feeling Abnormal: 7 people, 50.00%
Stress And Anxiety: 7 people, 50.00%
Drowsiness: 6 people, 42.86%
Pain: 5 people, 35.71%
Fatigue (feeling of tiredness): 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 5 people, 35.71%
Retching (strong involuntary effort to vomit): 4 people, 28.57%
Feeling Cold: 4 people, 28.57%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 28.57%
High Blood Pressure: 4 people, 28.57%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 28.57%
High Blood Pressure: 3 people, 21.43%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 14.29%
Pain: 2 people, 14.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 14.29%
Urine Output Decreased: 1 person, 7.14%
Urinary Tract Infection: 1 person, 7.14%
Oral Herpes (viral infection of mouth): 1 person, 7.14%
Oedema Peripheral (superficial swelling): 1 person, 7.14%
Muscle Spasms (muscle contraction): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Estradiol and have Affect lability?

- Check whether Affect lability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estradiol:

Estradiol (18,986 reports)

Affect lability treatments and more:

Affect lability (13,491 reports)

Browse all side effects of Estradiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Affect lability:

Affect lability (667 drugs)

Browse all the conditions that are associated with Affect lability:

Affect lability (830 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estradiol) and Estradiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.