Megestrol acetate and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Megestrol acetate (megestrol acetate) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include drug ineffective among females and acute graft versus host disease in liver among males.

The phase IV clinical study analyzes what interactions people have when they take Megestrol acetate and Adderall. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Megestrol acetate?

Megestrol acetate has active ingredients of megestrol acetate. It is often used in appetite - decreased. eHealthMe is studying from 5,427 Megestrol acetate users. Check the latest studies of Megestrol acetate.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.



On Jul, 19, 2026

17 people who take Megestrol acetate and Adderall together, and have interactions are studied.

Megestrol acetate and Adderall drug interactions.

What are the common drug interactions of Megestrol Acetate and Adderall, by gender? *:

female:

  1. Drug ineffective
  2. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  3. Fatigue (feeling of tiredness)
  4. Fibromyalgia (a long-term condition which causes pain all over the body)
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  7. Hysterectomy
  8. Limb injury
  9. Lower limb fracture
  10. Muscle spasms (muscle contraction)

male:

  1. Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
  2. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  3. Fungal infection
  4. Hepatotoxicity (chemical-driven liver damage)
  5. Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Megestrol Acetate and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Fall
  2. Abdominal pain upper
  3. Bone pain
  4. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
  5. Diarrhoea
  6. Drug ineffective
  7. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  8. Fatigue (feeling of tiredness)
  9. Fibromyalgia (a long-term condition which causes pain all over the body)
  10. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

50-59:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Rib fracture
  3. Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
  4. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  5. Dyskinesia (abnormality or impairment of voluntary movement)
  6. Fungal infection
  7. Hepatotoxicity (chemical-driven liver damage)
  8. Loss of consciousness
  9. Migraine (headache)

60+:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 70.59%
  2. Premenstrual Syndrome: 1 person, 5.88%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.88%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.88%
  6. Birth Control: 1 person, 5.88%
  7. Bipolar Disorder (mood disorder): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Megestrol acetate and Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Megestrol acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Megestrol acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on megestrol acetate and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Megestrol acetate and Adderall, respectively), and Megestrol acetate and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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