Melatonin and Coconut oil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Coconut oil (coconut oil). Common drug interactions include dry skin among females and mental status changes among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Coconut oil. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Coconut oil?

Coconut oil has active ingredients of coconut oil. eHealthMe is studying from 1,042 Coconut oil users. Check the latest studies of Coconut oil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

76 people who take Melatonin and Coconut oil together, and have interactions are studied.

Melatonin and Coconut oil drug interactions.

What are the common drug interactions of Melatonin and Coconut Oil, by gender? *:

female:

Dry skin
Epistaxis (bleed from the nose)
Feeling hot
Gait disturbance
Hallucination (an experience involving the perception of something not present)
Heart rate irregular
Hyperventilation
Hypoaesthesia (reduced sense of touch or sensation)
Lymphoedema (localized fluid retention and tissue swelling)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)

male:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Productive cough
Skin disorder (skin disease)
Stupor (lack of critical cognitive function and level of consciousness)
Unresponsive to stimuli
Urine output decreased
Cold sweat
Consciousness fluctuating
Dementia (madness)
Feeling cold

What are the common drug interactions of Melatonin and Coconut Oil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Respiratory disorder (respiratory disease)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)

10-19:

Anaemia (lack of blood)
Contusion (a type of hematoma of tissue in which capillaries)
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Iron binding capacity total decreased
Transferrin decreased
Transferrin saturation decreased

20-29:

n/a

30-39:

n/a

40-49:

Fall
Head injury
Pain
Pain in extremity
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Activities of daily living impaired
Depression
Frustration (a form of poorly expressed anger)
Impaired work ability
Migraine (headache)

50-59:

Heart rate irregular
Hyperventilation
Hypoaesthesia (reduced sense of touch or sensation)
Lymphoedema (localized fluid retention and tissue swelling)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myalgia (muscle pain)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)

60+:

Diarrhoea
Fatigue (feeling of tiredness)
Parkinson's disease
Skin disorder (skin disease)
Stupor (lack of critical cognitive function and level of consciousness)
Unresponsive to stimuli
Urine output decreased
Visual impairment
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cold sweat

What are the existing conditions these people have? *

Sleep Disorder: 9 people, 11.84%
Breast Cancer: 8 people, 10.53%
Parkinson's Disease: 7 people, 9.21%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 9.21%
Multiple Myeloma (cancer of the plasma cells): 7 people, 9.21%
Rash - Child Under 2 Years: 6 people, 7.89%
Osteoporosis (bones weak and more likely to break): 6 people, 7.89%
Constipation: 6 people, 7.89%
Dementia (madness): 6 people, 7.89%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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