Melatonin and Gemtesa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Gemtesa (vibegron). Common drug interactions include formication among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Gemtesa. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Gemtesa?

Gemtesa has active ingredients of vibegron. eHealthMe is studying from 2,648 Gemtesa users. Check the latest studies of Gemtesa.

On Jul, 07, 2026

34 people who take Melatonin and Gemtesa together, and have interactions are studied.

Melatonin and Gemtesa drug interactions.

What are the common drug interactions of Melatonin and Gemtesa, by gender? *:

female:

Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Hallucination (an experience involving the perception of something not present)
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Hypersensitivity
Hypersomnia (excessive daytime sleepiness (eds))
Incontinence (lack of moderation or self-control)
Intervertebral disc protrusion (spinal disc protrusion)
Lacrimation increased
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Psychomotor hyperactivity (feelings of extreme restlessness)

male:

Rash
Dizziness
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site reaction
Injection site swelling
Joint injury
Memory impairment
Nasopharyngitis (inflammation of the nasopharynx)
Peripheral swelling

What are the common drug interactions of Melatonin and Gemtesa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Restlessness (not able to rest)

30-39:

n/a

40-49:

Acne (skin problems that cause pimples)
Scab (a hard coating on the skin formed during the wound healing)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Drug ineffective
Dry mouth
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Hypersensitivity
Lacrimation increased
Rash
Rash pruritic (redness with itching)

50-59:

Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)
Drug hypersensitivity
Eye pain
Hypersomnia (excessive daytime sleepiness (eds))
Sinusitis (inflammation of sinus)

60+:

Headache (pain in head)
Dyspnoea (difficult or laboured respiration)
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Heart rate decreased
Heart rate irregular
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Injection site discharge
Injection site erythema (redness at injection site)
Injection site pain

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 20.59%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 11.76%
Parkinson's Disease: 4 people, 11.76%
Osteoporosis (bones weak and more likely to break): 4 people, 11.76%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 4 people, 11.76%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 3 people, 8.82%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 5.88%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 5.88%
Incontinence (lack of moderation or self-control): 2 people, 5.88%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and Gemtesa?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously