Melatonin and Noctiva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Noctiva (desmopressin acetate). Common drug interactions include sneezing among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Noctiva. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,213 Melatonin users. Check the latest studies of Melatonin.

What is Noctiva?

Noctiva has active ingredients of desmopressin acetate. eHealthMe is studying from 520 Noctiva users. Check the latest studies of Noctiva.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

11 people who take Melatonin and Noctiva together, and have interactions are studied.

Melatonin and Noctiva drug interactions.

What are the common drug interactions of Melatonin and Noctiva, by gender? *:

female:

Sneezing
Anxiety
Arthralgia (joint pain)
Cellulitis (infection under the skin)
Fatigue (feeling of tiredness)
Headache (pain in head)
Incontinence (lack of moderation or self-control)
Oral pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Therapeutic response unexpected

male:

Drug ineffective
Nasal discomfort
Nocturia (the need to get up in the night to urinate)
Back pain
Decreased appetite
Upper-airway cough syndrome
Lacrimation increased
Fatigue (feeling of tiredness)
Sinus pain

What are the common drug interactions of Melatonin and Noctiva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Drug ineffective
Nasal discomfort
Headache (pain in head)
Incontinence (lack of moderation or self-control)
Lacrimation increased
Oral pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Therapeutic response unexpected
Instillation site pain
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Urination - Excessive At Night: 6 people, 54.55%
Micturition Urgency (urgency to pass the urine): 2 people, 18.18%
Urethral Stenosis (narrowing of the urethra, may cause decreased urine output): 1 person, 9.09%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 1 person, 9.09%
Memory Loss: 1 person, 9.09%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 9.09%
Enlarged Prostate: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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