Mellaril and Folic acid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Mellaril (thioridazine hydrochloride) and Folic acid (folic acid). Common drug interactions include type 2 diabetes mellitus among females and agranulocytosis among males.
The phase IV clinical study analyzes what interactions people have when they take Mellaril and Folic acid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Mellaril?
Mellaril has active ingredients of thioridazine hydrochloride. eHealthMe is studying from 1,516 Mellaril users. Check the latest studies of Mellaril.
What is Folic acid?
Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,025 Folic acid users. Check the latest studies of Folic acid.
14 people who take Mellaril and Folic acid together, and have interactions are studied.

What are the common drug interactions of Mellaril and Folic Acid, by gender? *:
female:
- Type 2 diabetes mellitus
- Conjunctival abrasion (injury to outer surface of eye)
- Dizziness
- Exostosis (formation of new bone on the surface of a bone)
- Furuncle (infection of the hair follicle)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Melaena (the passage of black, tarry stools)
- Neck pain
- Neuropathy peripheral (surface nerve damage)
- Otitis externa (external ear infection)
male:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Antisocial behaviour
- Constipation
- Diarrhoea
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Pain
- Alopecia (absence of hair from areas of the body)
- Breast enlargement
- Breast neoplasm (non cancerous tumour of breast)
- Delusion (a false belief or opinion)
What are the common drug interactions of Mellaril and Folic Acid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Alopecia (absence of hair from areas of the body)
- Breast enlargement
- Breast neoplasm (non cancerous tumour of breast)
40-49:
- Constipation
- Diarrhoea
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Pain
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetes mellitus inadequate control
- Diabetic nephropathy (diabetic kidney disease)
- Type 2 diabetes mellitus
- Weight increased
50-59:
- Conjunctival abrasion (injury to outer surface of eye)
- Dizziness
- Exostosis (formation of new bone on the surface of a bone)
- Furuncle (infection of the hair follicle)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Melaena (the passage of black, tarry stools)
- Neck pain
- Neuropathy peripheral (surface nerve damage)
- Otitis externa (external ear infection)
- Otitis media (inflammation of the middle ear)
60+:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Antisocial behaviour
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Conjunctivitis (pink eye)
- Delusion (a false belief or opinion)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Drug level increased
- Enuresis (repeated inability to control urination)
- Hallucination, tactile (sensation of physical contact with an object that isn't there)
- Hypomania (a mild form of mania, marked by elation and hyperactivity)
What are the existing conditions these people have? *
- Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 21.43%
- Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 21.43%
- Bipolar Disorder (mood disorder): 3 people, 21.43%
- Depression: 2 people, 14.29%
- Stress And Anxiety: 1 person, 7.14%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 7.14%
- Rashes (redness): 1 person, 7.14%
- Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
- Nausea (feeling of having an urge to vomit): 1 person, 7.14%
- High Blood Cholesterol: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Mellaril and Folic acid?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Mellaril (1,516 reports)
- Folic acid (165,025 reports)
Browse all drug interactions of Mellaril and Folic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mellaril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Folic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mellaril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Folic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on thioridazine hydrochloride and folic acid (the active ingredients of Mellaril and Folic acid, respectively), and Mellaril and Folic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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