Melphalan and Zocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melphalan (melphalan) and Zocor (simvastatin). Common drug interactions include neuropathy peripheral among females and haematuria among males.

The phase IV clinical study analyzes what interactions people have when they take Melphalan and Zocor. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Melphalan?

Melphalan has active ingredients of melphalan. eHealthMe is studying from 20,052 Melphalan users. Check the latest studies of Melphalan.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

21 people who take Melphalan and Zocor together, and have interactions are studied.

What are the common drug interactions of Melphalan and Zocor, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Pain in extremity
Abdominal distension
Anxiety
Arthralgia (joint pain)
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Haematuria (presence of blood in urine)
Tricuspid valve incompetence (inefficient heart valve)
Osteolysis (dissolution of bone)
Osteonecrosis of jaw (death of bone of jaw)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Plasma cell myeloma (cancer that begins in plasma cells)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Skin fibrosis (fibrous tissue formation on skin)

What are the common drug interactions of Melphalan and Zocor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Arthralgia (joint pain)
Bone disorder
Deformity (disfigurement)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fall
Infection
Leukopenia (less number of white blood cells in blood)
Mucosal inflammation (infection of mucous membrane)

50-59:

Anaemia (lack of blood)
Decreased appetite
Feeling cold
Nausea (feeling of having an urge to vomit)

60+:

Haematuria (presence of blood in urine)
Tricuspid valve incompetence (inefficient heart valve)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Depression
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Herpes zoster
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Neuropathy peripheral (surface nerve damage)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 18 people, 85.71%
Nausea (feeling of having an urge to vomit): 3 people, 14.29%
Nausea And Vomiting: 2 people, 9.52%
Insomnia (sleeplessness): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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